Protein Alignment: Ca-beta and cacnb3

• Sequence 1: NP_001260375.1
• Gene: Ca-beta
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_012811901.1
• Gene: cacnb3
• XenbaseID: XB-GENE-1011906
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 278/520 (53%)
• Similarity: 348/520 (67%)
• Gaps: 76/520 (15%)

  Fly    41 GSADSNYSQPS--SDLSLDEEKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPV 103
            |||||..|:||  ||:||:|::|:.|||.||||..||::||.|||||||||||:|.||:|::.||
 Frog    16 GSADSYTSRPSLDSDVSLEEDRETARREVERQAQEQLERARLKPVAFAVRTNVSYCGALDEECPV 80

  Fly   104 QGGAVSFEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSS 168
            ||.|::||.::||||||||:|:||:|||||||.|:.|||||.:|:.||::.:.:..|      |.
 Frog    81 QGAAINFEAKDFLHIKEKYNNDWWVGRLVKEGADITFIPSPQRLEAIRLKQEQKARR------SG 139

  Fly   169 SGNLGAGGQAGAEPSRGSTPPTPGDESDSMGPGRHGKTPAAAANKEKRKPFFKKQETASPYDVVP 233
            .|::.:|       :|.|.||       ||.             |:|:    |:.|..:||||||
 Frog   140 GGDMVSG-------NRRSPPP-------SMA-------------KQKQ----KQAEHIAPYDVVP 173

  Fly   234 SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAIMER 298
            |||||||||||||||||||||||||||||||||:|||.||||.||:||||||::|||.||||:||
 Frog   174 SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRAIIER 238

  Fly   299 SSSRSDCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQRLI 363
            ||:||. :.:||.|||||||||::||||:||.||||||:||:||||||.||::|:||.|||||||
 Frog   239 SSTRSS-IAEVQSEIERIFELAKTLQLVILDADTINHPTQLSKTSLAPIIVFVKVSSPKVLQRLI 302

  Fly   364 KSRGKSQAKNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACEHIAEYLETYWKATHPDIR---- 424
            |||||||.|:|:|||:||:||.||||::||||||||||||||||:|||:|.||:|||..:.
 Frog   303 KSRGKSQVKHLNVQMLAADKLIQCPPELFDVILDENQLEDACEHLAEYMEVYWRATHHPLHPQNS 367

  Fly   425 ---AVPPIARPLPQEASPSADPARLGPTPPVDGEEFVDEQDPRMGMSGGDREGSRERDRDSRERE 486
               ..||.|.|..|:....:|.|         .|....|:|..| .|....|.||:....|.:|.
 Frog   368 QNLITPPTAIPGLQDQQLLSDRA---------NEHSPLERDSLM-QSDEASETSRKTWTASSQRS 422

  Fly   487 R---ERERERDYWD-----REFN------RDRSSKDR--ERDLEWERERAREWERERERDWDRE 534
            .   |.|....|.|     |..|      ....|:||  |||.| :....|.|  :|.|.|.::
 Frog   423 SHHLEDEYSDTYTDLYQPHRHHNSGLNSTNGHDSQDRLLERDSE-QNHNDRNW--QRNRPWPKD 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	25/42 (60%)
		SH3_CACNB	85..146	CDD:212797	42/61 (69%)
		Guanylate_kin	234..415	CDD:279019	144/181 (80%)
		NK	244..416	CDD:302627	135/172 (78%)
cacnb3	XP_012811901.1	VGCC_beta4Aa_N	16..58	CDD:288872	25/42 (60%)
		SH3_CACNB3	58..125	CDD:212975	47/67 (70%)
		Guanylate_kin	174..354	CDD:279019	144/181 (80%)
		NK	184..355	CDD:302627	135/172 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C52550055
eggNOG	1	0.900				E1_KOG3812
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000450
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.889	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	5	4.700