Protein Alignment l(2)gd1 and cc2d1b

DIOPT Version :10

• Sequence 1: NP_001245976.1
• Gene: l(2)gd1 / 34543
• FlyBaseID: FBgn0261983
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: XP_004914063.2
• Gene: cc2d1b / 100489497
• XenbaseID: XB-GENE-997988
• Length: 864
• Species: Xenopus tropicalis
• Alignment Length: 868
• Identity: 291/868 - (33%)
• Similarity: 461/868 - (53%)
• Gaps: 106/868 - (12%)

  Fly    25 IPDDFDPSAGYGEDDGGDSDLEAELAAITGGEGA-KPKPKPKAKLLPASDLDKMIADSLRDVSDD 88
            ||||        .||..|.||||||||:||.:.| |||||.||. ||..|::||..|.::|...:
 Frog    39 IPDD--------PDDPDDGDLEAELAALTGVKAASKPKPKGKAP-LPMEDIEKMAQDCMKDTIGE 94

  Fly    89 DDDDNLESDPDLLGELSGIGGLEEAEEEEPVAQPPAASEEP------------------VQTFLP 135
            |||::||.|.:||.||..:.|.:|.||.|.:....|...||                  :|..|.
 Frog    95 DDDEDLEGDEELLAELQEVVGDDEEEEMEQLRPSNAEELEPPLPDILESGQQVNSSATEIQHHLQ 159

  Fly   136 TTTVDTLSIIKQRLEMYKQAEANAKTAGDSGKARRFGRGLKTLKDLHRQAAAGKSINVDDIPPEV 200
            ........::::|:..||:|.:|||.:.:|.||||:.||||||:.:......|:::...||||.|
 Frog   160 APAEGMFQVLEERIRNYKEAISNAKLSNESAKARRYERGLKTLESMLHTVKQGRAVIEADIPPPV 224

  Fly   201 SV-KPIGGQAPPVPAEES-----------PAPSTPA------SPPPVPSRAAPDPPTPGTPVEPT 247
            :. ||.......||..::           |..:|.|      |..||......|    |..|:.|
 Frog   225 ACGKPAVSPKTDVPTTDTSKEEVEDLNHVPMETTEAATNLDSSEDPVSKAITND----GGAVDKT 285

  Fly   248 TSVAPTSPPNPLVTQMRSRQTDYKAAALQSKRSGDISTALQFLKVVKQFDVVIKMCEDGQEVDLS 312
            .. ||.:..:| .|.:..||.:||.|||:||::|:|..|.:::::.|:|.||::..|.||.||||
 Frog   286 HG-APQNDTDP-KTLLLQRQREYKLAALKSKQTGNIEKAKEYMRISKKFSVVLEALESGQPVDLS 348

  Fly   313 DMPPPPAEFLEFLKKMQEEAAAEAVAEPTAAPEPTPVAPAPVLAAATNMLEALQQRLEKYQSVEA 377
            :||..|.:....:.:      ::..|.||.|| |.||:....|:|. ::|:|||||:|||:|...
 Frog   349 NMPAAPEDHDTMVTE------SKIPAHPTPAP-PVPVSNTQGLSAG-SLLQALQQRMEKYKSAAQ 405

  Fly   378 AAKAENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELPVPPGFGPLPTADAAPVAPTPSLPTS 442
            .||:..:..|||...||.|||:|||:.:|||:.|...||||||||.|||..:  ......|:..:
 Frog   406 QAKSSGDDRKARMHERIAKQYQDAIRAHKAGRQVNLAELPVPPGFPPLPGME--QTEEEGSVEKA 468

  Fly   443 PTSPPPTASTSAGGTPSSSSATTPTAPRKAPSPPKPKELT-------------------TRTSGN 488
            ..:....|.| ||...............|.|..|||.:|.                   .:|:..
 Frog   469 LEAAQKLAKT-AGNEEDDDDGEEGECQAKPPGHPKPTQLVKPMPAVSDSEETSLTNKAPVKTASE 532

  Fly   489 QQKNNIAEQQMKLLLERQKEFKLAAIEAKKAGEIDQAKEYLKIFKGFDSLLNAASSGLPVDLSTL 553
            ::.....::|::.|..|:|:::.||::||:..:::|||:::::.......::...||..||:|.:
 Frog   533 EKLPPAVQEQLEFLEHRKKQYRKAALQAKQKNDLEQAKQHMRVAHTLQVSIDQVRSGKLVDISKV 597

  Fly   554 PVPPSQRDNLEASFAIVSAEECDPTDDICEIGVRMEEQLAKQLMMCKNTRDHHKAMGDVAGMNRF 618
            |..|   |:.|:.|.:|..|:.....:..::...:.:.|.:|...|.........||:||...||
 Frog   598 PSLP---DDEESDFVVVEHEDIKTPQNSEDVYSMLLKLLHEQHEKCIRYSKQFTQMGNVAETTRF 659

  Fly   619 ENLALTVQKDLDLVRYSKRKNEPLPKFHYEKRSFNIVHCNTDLTDSELEIVVVRGISYNVAN--- 680
            |.:|...:|:.::::.|:.:....|.:|:|.::..||...::|:.:|:.:::||||:....:
 Frog   660 EKMAEDCKKNCEILQLSQAQGLDPPPYHFEDKTLKIVRVFSELSSTEMLLIIVRGINLPAPSGVA 724

  Fly   681 PKDVDTYVRVEFPLLNDES-FKTKTNVIRDTSSPDYDERFKVDIQRTNRQFQRIFKRHGVKFEIY 744
            |.|:|.||:.|||..:.|. .|.||.||::|:||:|:..||::|.|.:|.|:|:.:..|:||||:
 Frog   725 PNDLDAYVKFEFPYPSSEQPQKNKTLVIKNTNSPEYEHSFKLNINRNHRGFKRVIQTKGIKFEIF 789

  Fly   745 SRGCSIDCCGLSRKLPLCCFRGFLRSDTLIGTVNVKLQPLETKCEIHDTYDLMDGRKQVGGKLEV 809
            .:|..:                 :|||..:||.:|||..|||:|||.:..::.||||..|||||:
 Frog   790 HKGFFL-----------------VRSDKQVGTASVKLDKLETQCEIREIVEVFDGRKPTGGKLEI 837

  Fly   810 KIRVRNPILTKQMEHITEKWLVL 832
            |:|:|:|:..:.::.:||||||:
 Frog   838 KVRLRDPLNGQDLQVVTEKWLVM 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)gd1	NP_001245976.1	DM14	142..200	CDD:128928	23/57 (40%)
		DM14	260..318	CDD:128928	26/57 (46%)
		DM14	362..420	CDD:128928	31/57 (54%)
		DM14	499..557	CDD:128928	16/57 (28%)
		C2_Freud-1	661..832	CDD:176072	69/174 (40%)
cc2d1b	XP_004914063.2	DM14	169..224	CDD:128928	23/54 (43%)
		DM14	297..354	CDD:128928	26/56 (46%)
		DM14	390..443	CDD:128928	27/52 (52%)
		DM14	543..601	CDD:128928	16/57 (28%)
		C2_Freud-1	702..860	CDD:176072	69/174 (40%)