Protein Alignment piwi and AGO5

DIOPT Version :10

• Sequence 1: NP_476875.1
• Gene: piwi / 34521
• FlyBaseID: FBgn0004872
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_850110.1
• Gene: AGO5 / 817334
• AraportID: AT2G27880
• Length: 997
• Species: Arabidopsis thaliana
• Alignment Length: 1061
• Identity: 234/1061 - (22%)
• Similarity: 397/1061 - (37%)
• Gaps: 304/1061 - (28%)

  Fly     5 QGRGRRRPLNEDDS------------------STSRGSGDGPRVKVFRGSSSGDPRA-------- 43
            :|.|||....:|.|                  |.|.|.|.|   .|.||.::||..|
plant    16 RGGGRRSDQRQDQSSGQVAWPGLQQSYGGRGGSVSAGRGRG---NVGRGENTGDLTATQVPVASA 77

  Fly    44 -----------DPRIEASRERRAL-------EEAPRREGG---------PTERKPWGDQYDYLNT 81
                       ||....:...:.:       ||:...|..         .||.||     :..:.
plant    78 VSGGRGRGNIGDPTFSVASSSKTVSVASSSKEESKNTEVSETMSNLQITSTETKP-----EMTSL 137

  Fly    82 RPAELVSK---------KGTDGVPVMLQTNFFRLKTKPEWRIVHYHVEFEPSIENPRVRMGVLS- 136
            .||.  ||         :||.|..||::.|.|.::. .:..:.||.|...|.:.:..|...|:.
plant   138 PPAS--SKAVTFPVRPGRGTLGKKVMVRANHFLVQV-ADRDLYHYDVSINPEVISKTVNRNVMKL 199

  Fly   137 -----NHANLLGSGYLFDGLQ-LFTT--RKFEQEITVLS-------GKSKLDIEYKISIKFVGFI 186
                 ..::|.|....:||.: |:|.  ..|:.:..|::       |.|..|..:|:::|.|...
plant   200 LVKNYKDSHLGGKSPAYDGRKSLYTAGPLPFDSKEFVVNLAEKRADGSSGKDRPFKVAVKNVTST 264

  Fly   187 SCAE-PRFL------------QVLNLILRRSMKGLNLELVGRNLFDPRAKIEIREFKMEL----- 233
            ...: .:||            |||:::||..... :...|||:.|......:.|:.:.||
plant   265 DLYQLQQFLDRKQREAPYDTIQVLDVVLRDKPSN-DYVSVGRSFFHTSLGKDARDGRGELGDGIE 328

  Fly   234 -WPGYETSIRQHEKDILLGTEITHK-----VMRTETIYDIMR-RCSHNPARHQDEVRV-NVLDLI 290
             |.||..|:|..:..:.|..:::.:     ::.|:.|...:. |..:.|.|..|.::| .||
plant   329 YWRGYFQSLRLTQMGLSLNIDVSARSFYEPIVVTDFISKFLNIRDLNRPLRDSDRLKVKKVL--- 390

  Fly   291 VLTDYNNRTYRINDVDFGQTPKSTFSCKG------RDISF----------VEYYLTKYNIRIRDH 339
                   ||.::..:.:..|..:..|  |      |::.|          |:|:..|||.|::..
plant   391 -------RTLKVKLLHWNGTKSAKIS--GISSLPIRELRFTLEDKSEKTVVQYFAEKYNYRVKYQ 446

  Fly   340 NQPLLISKNRDKALKTNASELVVLIP-ELCRVTGLNAEMRSNFQLMRAMSSYT-RMNPKQRTDRL 402
            ..|         |::|.:....|.:| |||::.              ....|| |:|.||.|..|
plant   447 ALP---------AIQTGSDTRPVYLPMELCQID--------------EGQRYTKRLNEKQVTALL 488

  Fly   403 RAFNHRLQNTPESVKVL-----------RDWNMELDKNVTEVQGRIIGQQNIVFH-NGKVPAGEN 455
            :|...|..:...|:|.|           :::.|.:...:..::.|::....:.:| :||......
plant   489 KATCQRPPDRENSIKNLVVKNNYNDDLSKEFGMSVTTQLASIEARVLPPPMLKYHDSGKEKMVNP 553

  Fly   456 ADWQRHFRDQRMLTTPSDGLDRWAVIA---------PQRNSHELRTLLDSLYRAASGMGLR---- 507
            ...|.:..|::|:....  :..|..::         ||....:|..:.     .:.||..:
plant   554 RLGQWNMIDKKMVNGAK--VTSWTCVSFSTRIDRGLPQEFCKQLIGMC-----VSKGMEFKPQPA 611

  Fly   508 ---IRSPQEFIIYDDRTGTYVRAMDDCVRSDP--KLILCLVPNDNAERYSSIKK-----RGYVDR 562
               |..|.|.|         ..|:.|..:..|  :|::.::| |....|..||:     .|.|.:
plant   612 IPFISCPPEHI---------EEALLDIHKRAPGLQLLIVILP-DVTGSYGKIKRICETELGIVSQ 666

  Fly   563 AV-PTQVVTLKTTKNRSLMSIATKIAIQLNCKLG------------YTPWMIELPLSGLMTIGFD 614
            .. |.||..|    |:..|.   .:|:::|.|.|            ..|.:.:.|   .:.:|.|
plant   667 CCQPRQVNKL----NKQYME---NVALKINVKTGGRNTVLNDAIRRNIPLITDRP---TIIMGAD 721

  Fly   615 IA--KSTRDRKRAYGALIASMDLQQNSTYFSTVTECSAFDVLANTLWPMIAKALRQYQH-----E 672
            :.  :...|...:..|::||||..:.:.|...|:..:..:.:...|:.::....|...|     |
plant   722 VTHPQPGEDSSPSIAAVVASMDWPEINKYRGLVSAQAHREEIIQDLYKLVQDPQRGLVHSGLIRE 786

  Fly   673 H--------RKLPSRIVFYRDGVSSGSLKQLFEFE---VKDIIEKLKTEYARVQLSPPQLAYIVV 726
            |        .::|.||:|||||||.|...|:...|   ::.....|:..|.      |::.:::|
plant   787 HFIAFRRATGQIPQRIIFYRDGVSEGQFSQVLLHEMTAIRKACNSLQENYV------PRVTFVIV 845

  Fly   727 TRSMNTRFF--LNGQ--------NPPPGTIVDDVITLPERYDFYLVSQQVRQGTVSPTSYNVLYS 781
            .:..:||.|  .:|.        |..|||:||..|..|..:||||.|....|||..|..|:||..
plant   846 QKRHHTRLFPEQHGNRDMTDKSGNIQPGTVVDTKICHPNEFDFYLNSHAGIQGTSRPAHYHVLLD 910

  Fly   782 SMGLSPEKMQKLTYKMCHLYYNWSGTTRVPAVCQYA-----------------------KKLATL 823
            ..|.:.:::|.||..:|:.|...:.:..:.....||                       :...|.
plant   911 ENGFTADQLQMLTNNLCYTYARCTKSVSIVPPAYYAHLAAFRARYYMESEMSDGGSSRSRSSTTG 975

  Fly   824 VG---TNLHSIPQNALEKKFY 841
            ||   :.|.:|..|..|..||
plant   976 VGQVISQLPAIKDNVKEVMFY 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
piwi	NP_476875.1	PAZ	262..396	CDD:198017	33/153 (22%)
		Piwi_piwi-like_Euk	382..826	CDD:240016	121/546 (22%)
AGO5	NP_850110.1	PLN03202	131..997	CDD:215631	210/943 (22%)