DRSC/TRiP Functional Genomics Resources

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Protein Alignment YL-1 and Vps72

DIOPT Version :10

Sequence 1:NP_609475.1 Gene:YL-1 / 34516 FlyBaseID:FBgn0032321 Length:351 Species:Drosophila melanogaster
Sequence 2:NP_033362.2 Gene:Vps72 / 21427 MGIID:1202305 Length:368 Species:Mus musculus


Alignment Length:349 Identity:142/349 - (40%)
Similarity:194/349 - (55%) Gaps:49/349 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAASRSRRNNAGNKIAHLLNEEEEDDFYKTSYGGFQEDEEDKEYE-QKDEEEDVVDSDFSIDEND 64
            :|..|:.|..|||:::.||..||||:||:|:||||.|:..|.||: .:.:.||.|||||.|||.|
Mouse     3 LAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGD 67

  Fly    65 EPVSDQEEAPEKKRKRGVVNTKAYKETKPAVKKETKATPALHKKRPGGGVTKRRPRPRFTVL--- 126
            ||.|| .||.|.:|||.|| ||||||...:::....:|||         .:.::.|...|:|   
Mouse    68 EPSSD-GEAEEPRRKRRVV-TKAYKEPLKSLRPRKVSTPA---------SSSQKAREEKTLLPLE 121

  Fly   127 --DSG---RKSIRTSTAIKTQATKIRLKELDDARKRKKKKVRVEDYMPTQEELLEEAKITEEENT 186
              |.|   |||:|.|||..|:.|.:|::| ...:.|::|....|..: ||||||.|||||||.|.
Mouse   122 LQDDGSDSRKSMRQSTAEHTRQTFLRVQE-RQGQSRRRKGPHCERPL-TQEELLREAKITEELNL 184

  Fly   187 KSLEKFQKMELEKKKSRPTKRTFSGPTIRYHSLTMPAMRKP--------TRGANPAVDSKDLA-- 241
            :|||.::::|.:|||....||...||.|.|||:|:|.:.:|        ..|.:||..:..||  
Mouse   185 RSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDVEGLDPAPTASALAPH 249

  Fly   242 -------------GKCERTFVTIENDFNDKVFQSLFRHKAPPKAS-NGICPITRLPARYFDPITQ 292
                         ..|.|||:|..   :|..|:..|....|||.. ..:||:|..||.|.||:|.
Mouse   250 AGTGTGAAAATPPAHCSRTFITFS---DDATFEEWFPQGRPPKVPVREVCPVTHRPALYRDPVTD 311

  Fly   293 QPYYSIQAFKILREAYYMQLEQQG 316
            .||.:.:||||:||||...:...|
Mouse   312 IPYATARAFKIIREAYKKYITAHG 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
YL-1NP_609475.1 YL1 5..218 CDD:461734 100/221 (45%)
YL1_C 276..304 CDD:198061 14/27 (52%)
Vps72NP_033362.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..164 73/172 (42%)
YL1 7..216 CDD:461734 100/221 (45%)
YL1_C 295..323 CDD:462412 14/27 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 339..361
Blue background indicates that the domain is not in the aligned region.

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