DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-3 and SmydA-2

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_649084.1	Gene:	SmydA-2 / 40075	FlyBaseID:	FBgn0036839	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	476	Identity:	129/476 - (27%)
Similarity:	223/476 - (46%)	Gaps:	36/476 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VCGRYLVAKGAIRGHGLLIEELPFAVGPKCNGPVVCLGCYE-----PNPDPEEELCSECGWPLC- 77
            |.||:|.|...|:....:::|.|..:|||.....:||||:.     ..|......||.|.||||
  Fly    56 VLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCG 120

  Fly    78 VECAQQADNAHFRLECSQLKDA--RARFFRLPSGSRHCPQLDC-IMPLRVLLAKEANPERWDNEV 139
            .||   .|:.|.:.||..:..:  :::...:|..........| ||.||.:..|:.:|:.: .::
  Fly   121 KEC---EDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAF-LKL 181

  Fly   140 APMEHHKEERQRDADVWHADRVNIAQYLRGPCQLANRFSEELIMQVVGVLEVNAFEARSPK-GYP 203
            ..:|.|.:|| .:..::...|.|:..:::....:.: :.|..|:::..:|:.|.||.|.|: ...
  Fly   182 YNLEDHLKER-LETPLYQVLRANLITFIKTVLGMKD-WPEMDILRIAAILDTNTFEVRQPRERRK 244

  Fly   204 LRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSYTYTLDGTAQRQKHLKQ 268
            :|.|:|...:::|:||||.....  .:...|...|...:.:|:.|..|||..|..|.||:.||:|
  Fly   245 IRALYPGAAMISHDCVPNMRHRF--DDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQ 307

  Fly   269 GKFFTCQCERCLDPTELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCANCGSDTSNADALAMLQ 333
            .|.|.|.|.||.||.|||:...:..|.:|..|..:...|......|.|..|....|..|.:....
  Fly   308 AKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDA 372

  Fly   334 SLQSEVNAV-QALPMAAKRLEEIERLLRKYKSLLHPLHFIATGLRQLLIEMYGRVQGYEMVQLPD 397
            .||.|:.:: :..|:|      :|..:.::::.||..:......:..|.::||...|:.|.:|..
  Fly   373 ELQQELESLDKTTPVA------LEEFIYRHRADLHETNTHILQAKYALTQLYGSAPGFAMEELSG 431

  Fly   398 HQLERKAELCRQVLRVLNTFEPGLSRTRAMNLYELHVPLV---LLAKSGFIAGKLKGGELRARLV 459
            ..|.||.:||.::|::.:.|:.|.|..|...|.::...||   |.:|...        :...:|.
  Fly   432 ESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDMEEALVTQALRSKDPL--------DCEEKLR 488

  Fly   460 DAIDLLKECVEILEFEDKSSQ 480
            :|.::|:|...|::.|.:..|
  Fly   489 NAAEMLREIRNIMKHEPEMQQ 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	11/44 (25%)
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:280009
SmydA-2	NP_649084.1	SET	<246..291	CDD:214614	12/46 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I1875
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
	6	5.970