DRSC/TRiP Functional Genomics Resources

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Protein Alignment SmydA-3 and Smyd2

DIOPT Version :10

Sequence 1:NP_609464.1 Gene:SmydA-3 / 34502 FlyBaseID:FBgn0262599 Length:507 Species:Drosophila melanogaster
Sequence 2:NP_081072.1 Gene:Smyd2 / 226830 MGIID:1915889 Length:433 Species:Mus musculus


Alignment Length:451 Identity:96/451 - (21%)
Similarity:153/451 - (33%) Gaps:155/451 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 AKGAI-------RGHGLLIEELPFAVGP---KCNGPVV------------CLGCYEPNPDPEEEL 68
            |:|.:       :|.||.... ||.||.   .|  |..            |..|:     ..:|.
Mouse     5 ARGGLERFCSAGKGRGLRALR-PFHVGDLLFSC--PAYACVLTVGERGHHCECCF-----ARKEG 61

  Fly    69 CSECGWPLC-------VECAQQADNAHFRLECSQLKDARARFFRLPSGSRHCPQLDCIMPLRVLL 126
            .|:||  .|       ||| |:.|....:||||.:         :..|....|.....:..|:|.
Mouse    62 LSKCG--RCKQAFYCDVEC-QKEDWPLHKLECSSM---------VVLGENWNPSETVRLTARILA 114

  Fly   127 AKEANPERWDNE----VAPMEHHKEERQRD-ADVWHADRVNIAQ----YLRGPCQLANRFSEELI 182
            .::.:|||..:|    |...|.|.::...: .|:..:|...:.|    ||..|       ....:
Mouse   115 KQKIHPERTPSEKLLAVREFESHLDKLDNEKKDLIQSDIAALHQFYSKYLEFP-------DHSSL 172

  Fly   183 MQVVGVLEVNAF----EARSPKGYPLRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLE 243
            :.:...:..|.|    |..|..|   ..:||...::.|:|.||.   |...:|....:||:.::.
Mouse   173 VVLFAQVNCNGFTIEDEELSHLG---SAIFPDVALMNHSCCPNV---IVTYKGTLAEVRAVQEIH 231

  Fly   244 EGQPLHHSYTYTLDGTAQRQKHLKQGKFFTCQCERCLDPTELGTHFSSLKCGQCAEGFQVPRQPT 308
            .|..:..||...|..|..|...|:...||||:|..|                             
Mouse   232 PGDEVFTSYIDLLYPTEDRNDRLRDSYFFTCECREC----------------------------- 267

  Fly   309 EPDTSWNCANCGSDTSNADALAMLQSLQSEVNAVQALPMAAKRLEEIERLLRKYKSLLHPLHFIA 373
                         .|.:.|      ..:.||..:.:.|.|    |.|..::|..::         
Mouse   268 -------------TTKDKD------KAKVEVRKLSSPPQA----EAIRDMVRYARN--------- 300

  Fly   374 TGLRQLLIEMYGRVQGYEMVQLPDHQLERKAELCRQVLRVLNTFEPGLSRTRAMNLYELHV 434
                  :||.:.|.:.|:.   |...|| ..||.::  ::.:.||..       |:|.||:
Mouse   301 ------VIEEFRRAKHYKS---PSELLE-ICELSQE--KMSSVFEDS-------NVYMLHM 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SmydA-3NP_609464.1 SET_SMYD <192..279 CDD:380997 27/90 (30%)
Smyd2NP_081072.1 SET_SMYD2 7..269 CDD:380979 71/336 (21%)
zf-MYND 52..90 CDD:460312 13/45 (29%)
TPR_10 388..422 CDD:463861
Blue background indicates that the domain is not in the aligned region.

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