Protein Alignment SmydA-3 and set-18

DIOPT Version :10

• Sequence 1: NP_609464.1
• Gene: SmydA-3 / 34502
• FlyBaseID: FBgn0262599
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_871849.1
• Gene: set-18 / 172949
• WormBaseID: WBGene00044070
• Length: 507
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 117/523 - (22%)
• Similarity: 196/523 - (37%)
• Gaps: 129/523 - (24%)

  Fly    24 LVAKGAIRG-HG-LLIEELPFA---VGPKCNGPVVCLGCYEPNPDPEEEL--CSECGWPL-C-VE 79
            ||.|..|.. |. :.|.|.|||   :.||.:  ..|..|.. .|.|.|:|  |..|.:.: | .|
 Worm    16 LVQKDEISSIHARIKIFETPFATQVLNPKVS--EFCANCLR-GPAPGEKLLRCGGCNFSMYCSKE 77

  Fly    80 CAQQADNAHFRLECSQLKDARARFFRLPSGSRHCPQLDCIMPLRVLLAK----EANPERWDNEV- 139
            |...|...| :.||.:||   |.|..||        |..::.|..::.:    |.|.::...|.
 Worm    78 CQATAWLVH-KPECKRLK---ASFPNLP--------LTEVLFLSKVIDRIQFLEKNGDKLGIEAE 130

  Fly   140 ----APMEHHKEERQRDADVWHADRV--NIAQYLRGPCQLANRFSEELI-----MQVVGVLEVNA 193
                :.::|..:.|..:..:.|.:::  .:..: ||         ||:|     ..|.....:|:
 Worm   131 RKFSSLVDHKVDIRDDEEKMAHFEKIFEKMGAF-RG---------EEMIEKGEFFDVFCKATINS 185

  Fly   194 FEARSPKGYPLRCLFPYTGI--LAHNCVPNTSRSIYPSEGYKIRLRAM---VDLEEGQPLHHSYT 253
            ....:..|..:..... .|:  ..|:|.|..|...   :||::.||.:   ||.|..:....||.
 Worm   186 HSIHTNAGNEVGMALD-LGVSKYNHSCRPTCSMVF---DGYRVCLRPLVPGVDAENTEEAFISYI 246

  Fly   254 YTLDGTAQRQKHLKQGKFFTCQCERCLDPTELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCAN 318
            ........|::.|....:|.|:|.||:||.:  ...::::|...|....:....||...:..|..
 Worm   247 DVGRSKYIRRRDLNSRWYFNCECTRCMDPED--DALTAIRCANPACDAPILTSETEEPMNIACEK 309

  Fly   319 CGS----DTSNADALAMLQSLQSEVN-----AVQALPMAAKRLEEIERLLRKYKSLLHPLHFIAT 374
            |.:    ||..| |...:::|.:..:     .::|||      .:::.||.|.:.:|||.:....
 Worm   310 CKTIVEEDTVKA-AQEYMKTLPASFDPKCPAEIEALP------GKLKELLAKAEQILHPSNVYVA 367

  Fly   375 GLRQLLIEMYG--------------------------RVQGYEMVQLPDHQLER--KAELCRQVL 411
            .||..|..:.|                          |..|::::.:....:|:  :.|......
 Worm   368 RLRTALFHVTGTLTMDNLSSMHTQIYNNYKMCFPKADRHVGFQLLHIVKALIEKDERDEAMPYAF 432

  Fly   412 RVLNTFE-------PGLSRTRAMNLY-ELHVP-----LVLLAKSGFIAGKLKGGELRARLVDAID 463
            ..:|.||       |...:|.|:..| |..:|     ||.|....           ..|.:|.:.
 Worm   433 DAMNIFEVCFGLDHPYYLQTLALWTYLEKKIPKSTEELVQLTNFS-----------DNRPIDIVS 486

  Fly   464 LLK 466
            |||
 Worm   487 LLK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_609464.1	SET_SMYD	<192..279	CDD:380997	21/91 (23%)
set-18	NP_871849.1	zf-MYND	49..90	CDD:460312	13/42 (31%)
		SET	82..274	CDD:394802	47/217 (22%)