DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-3 and smyd2

DIOPT Version :9

Sequence 1:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_002934751.2	Gene:	smyd2 / 100495522	XenbaseID:	XB-GENE-985583	Length:	430	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	65/294 - (22%)
Similarity:	102/294 - (34%)	Gaps:	72/294 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RGHGLLIEELPFAVGP---KCNGPVV------------CLGCYEPNPDPEEELCSECGWPLC--- 77
            :|.||.... |||:|.   .|  |..            |..|:     ..:|..|:||  .|
Frog    15 KGRGLKATR-PFALGELLFSC--PAYTYVLTVNERGNHCEFCF-----ARKEGLSKCG--KCKQA 69

  Fly    78 ----VECAQQADNAHFRLECSQLKDARARFFRLPSGSRHCPQLDCIMPLRVLLAKEANPERWDNE 138
                |:| |:.|....:||||.:         ...|...||.....:..|:|..::...||..:|
Frog    70 FYCNVDC-QKGDWPMHKLECSAM---------CTYGQNWCPSETVRLTARILAKQKTQTERTASE 124

  Fly   139 ----VAPMEHHKEERQRDADVWHADRVNIAQYLRGPCQLANRFSEELIMQVVGVLEVNAFEARSP 199
                |...|.|..:...:.          .:.::......:||..:.:.......:|..|...:.
Frog   125 RFLSVKDFESHLSKLDNEK----------LELIQNDIAALHRFYSKNLHYSDNAAQVFLFAQVNC 179

  Fly   200 KGYPLR---------CLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSYTYT 255
            .|:.:.         .:||...::.|:|.||.   |...:|....:||:.::..|..:..||...
Frog   180 NGFTIEDEELSHLGSAIFPDVALMNHSCCPNV---IVTYKGTVAEVRAVQEIHAGDEVFTSYIDL 241

  Fly   256 LDGTAQRQKHLKQGKFFTCQCERC----LDPTEL 285
            |..|..|...|....||.|.|..|    .||.:|
Frog   242 LYPTEDRNDRLIDSYFFNCDCRECSTKQKDPAKL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	11/44 (25%)
smyd2	XP_002934751.2	zf-MYND	50..88	CDD:280009	12/45 (27%)
		SET	145..238	CDD:279228	16/95 (17%)
		TPR_12	336..409	CDD:290160
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010