Protein Alignment Trim9 and Pml

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001414234.1
• Gene: Pml / 315713
• RGDID: 1562602
• Length: 886
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 108/581 - (18%)
• Similarity: 180/581 - (30%)
• Gaps: 243/581 - (41%)

  Fly     5 LRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGNGGGA 69
            ||||.|:.....|.||||.|.||.||   ::.|
  Rat    29 LRCPGCQTQAKCPKLLPCLHTLCSGC---LEAP-------------------------------- 58

  Fly    70 GGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCCSNTSR 134
              |...|:.  ..||             |:|..:|::.         ::|.|:
  Rat    59 --GLQCPIC--QAPG-------------SANANAEALD---------NVFFES------------ 85

  Fly   135 PVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREALR 199
                                         |.|:|..|              ..|||...|
  Rat    86 -----------------------------LQRRLAVF--------------RQIVDAQAA----- 102

  Fly   200 CQMCETDPKVASLICEQCEIRYCDACRE-----LTHPARGPLAK---HTLVKPRGAAQQRESVCG 256
            |..|:   ::|...|.:||...|..|.:     |.|.|| |||:   :::.:...:.::....|.
  Rat   103 CTRCK---ELADFWCFECEQLMCGKCFDAHQWYLKHEAR-PLAELRDNSVREFLDSTRKSNIFCS 163

  Fly   257 E-HEETLSQ---YCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTT 317
            . :..|.:|   ||..|..|.|..|....|:.:|      :.|     |:...:|||.|:..:.|
  Rat   164 NTNHRTPAQTNIYCRGCAKPLCCECALLDRNHSH------LQC-----EIGKEIQQLHEELGTMT 217

  Fly   318 EFIQ-----------RLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEA--IRMDKDT 369
            :.::           ::.....::.::..:.|:.:.|:...:|:.:..:...||||  :|..:|.
  Rat   218 QALEEQGRTFDSAHAQMHSAIGQLDDARSDTEKQIRARVRQVIEHVQAQERELLEAVNVRYQRDY 282

  Fly   370 K----------------------------------------------IRILKDQQSNCTGKLQ-Q 387
            :                                              .|:.:::..|  .|:| :
  Rat   283 QEIAGQLGHLEAVLQRIRTGGALVKRMKLYASEQEVLDMHGFLRKALCRLRQEEPQN--HKVQLR 345

  Fly   388 TTGLIQF--CIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALA 450
            |:|..:|  |::     |..:|:         ...||:.       .|.|.||....|..:||.|
  Rat   346 TSGFEEFKLCLQ-----DLVSFI---------TQRTDVA-------VAGRASPEAASTHPEAASA 389

  Fly   451 RAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPPNHSFVEGYVLEL 511
                     |..|.....|...|.|...:..|...|...||..:. ||......:...:||
  Rat   390 ---------QPEAASTHPEAASAQPEAASAHPESASTPGNSTDLE-QPKEVQRAQAQAMEL 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	15/29 (52%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	15/52 (29%)
		Bbox2_TRIM9-like	255..291	CDD:380822	11/39 (28%)
		CC_brat-like	298..420	CDD:475168	25/183 (14%)
		FN3	472..564	CDD:238020	10/40 (25%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947
Pml	NP_001414234.1	None