Protein Alignment Trim9 and Trim28

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_063121963.1
• Gene: Trim28 / 116698
• RGDID: 620289
• Length: 851
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 133/629 - (21%)
• Similarity: 230/629 - (36%)
• Gaps: 152/629 - (24%)

  Fly    42 SALPGAVNGAGAASAAGHNGLHGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGS--- 103
            :|...|.:.|.|||||  :|..|:|.|:.||...|..         ||.::|:::|||..|.
  Rat     6 AAATAAASAATAASAA--SGSPGSGEGSAGGEKRPAA---------SSAAAASASASSPAGGGGE 59

  Fly   104 ------------ESVTSDQDQSDKVSIFSEADSGVVCCSNTSRP--VSYAGTGLLPGVGNVVAPP 154
                        |.:..::|.    .:.....|....|...:.|  .:.:|.|...|.|.:|
  Rat    60 AQELLEHCGVCRERLRPERDP----RLLPCLHSACSACLGPATPAAANNSGDGGSAGDGAMV--- 117

  Fly   155 GAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREA------------LRCQMCETDP 207
                  .||:|::..:..|              ||:.:..|::            ..|..|| |.
  Rat   118 ------DCPVCKQQCYSKD--------------IVENYFMRDSGSKASSDSQDANQCCTSCE-DN 161

  Fly   208 KVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRES----VCGEHE-ETLSQYCL 267
            ..|:..|.:|....|:.|.| .| .|....|...|:..|.|:.|:.    .|..|: |.|..:|.
  Rat   162 APATSYCVECSEPLCETCVE-AH-QRVKYTKDHTVRSTGPAKTRDGERTVYCNVHKHEPLVLFCE 224

  Fly   268 SCKAPACGLCIGELR-HQAHDVQSINVTCKAQKTELSHNLQQLSEK----ARSTTEFIQRLKGMS 327
            ||....|..|  :|. |:.|..|.:....:.|:..|:..:::|.:|    .::|.|....::.:|
  Rat   225 SCDTLTCRDC--QLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKNTKEVRSSIRQVS 287

  Fly   328 D-------KVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKL 385
            |       .|..:.::..:.::.:...|:.......|...|.:.....|..:|.|.|:.
  Rat   288 DVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEH------ 346

  Fly   386 QQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTL--DDAA 448
                 :::|...||:..::.|.|....::..::       |:.:......|.|..::..  |..|
  Rat   347 -----ILRFASWALESDNNTALLLSKKLIYFQL-------HRALKMIVDPVEPHGEMKFQWDLNA 399

  Fly   449 LARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQPPNHSFVEGYVLELDD 513
            ..::.:  .|.::.|.:.|.......||.|...|...|.:.:..:   ||          :|:.:
  Rat   400 WTKSAE--AFGKIVAERPGTNSTGPGPMAPPRAPGPLSKQGSGSS---QP----------MEVQE 449

  Fly   514 GSGGEFREVYCGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSEL------IGLQTAEVAWFTF 572
            |.|....:.|...|.       |.:.|..:|      :||||.|.|      :.|:..::. .|.
  Rat   450 GYGFGTDDPYSSAEP-------HVSGMKRSR------SGEGEVSGLMRKVPRVSLERLDLD-LTS 500

  Fly   573 D---PVLSGGAGS-----GLIFSKNNATVSVEGWEHRVALGSVG 608
            |   ||.....||     .||..:..|..:..|....|..|:.|
  Rat   501 DSQPPVFKVFPGSTTEDYNLIVIERGAAAAAAGQAGTVPPGAPG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	14/44 (32%)
		Bbox2_TRIM9-like	255..291	CDD:380822	13/37 (35%)
		CC_brat-like	298..420	CDD:475168	21/132 (16%)
		FN3	472..564	CDD:238020	22/97 (23%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	14/56 (25%)
Trim28	XP_063121963.1	None