Protein Alignment Myo31DF and myo1b

DIOPT Version :10

• Sequence 1: NP_523538.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Sequence 2: XP_003199241.2
• Gene: myo1b / 541515
• ZFINID: ZDB-GENE-030131-695
• Length: 1165
• Species: Danio rerio
• Alignment Length: 1178
• Identity: 442/1178 - (37%)
• Similarity: 631/1178 - (53%)
• Gaps: 224/1178 - (19%)

  Fly     8 GVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFEN 72
            ||.|.|||:.:|.|.|::||:|||.:..||||||.|.:|||||:.::||..|.:.:|:.|..:|.
Zfish    13 GVGDMVLLEPLSEESFIENLKKRFDHNEIYTYIGSVVISMNPYKSLSIYSAEKVEEYRNRNFYEL 77

  Fly    73 APHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLI 137
            :||::|:||.|||.|:.:.:|.||||:||||||||||||.:|.|:|||. .:|| |:.:||..|:
Zfish    78 SPHIYALADEAYRSLRHQDKDQCILITGESGAGKTEASKFVMSYVAAVC-GKGQ-EVNKVKEQLL 140

  Fly   138 QSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSF 202
            |||.:||.||||||.|||||||||||||||||:|.||:||:|:||||||||||:|..||||||.|
Zfish   141 QSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHIF 205

  Fly   203 YQLLRGANDNELRQYELQKETGKYHYLNQGSMDI--LTEKSDYKGTCNAFKTLGFSTDEVQTIWR 265
            ||||.||:|:.|::.:|.::..||:||:..|..:  |.:.:.::...||.:.:||..||||:|..
Zfish   206 YQLLSGASDDMLKKLKLDRDFSKYNYLSLDSATVNGLDDAASFRTVRNAMQIVGFMEDEVQSILE 270

  Fly   266 TIAAVLHLGNVEFQTIE-----DELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQK 325
            .|||||.|||:||:...     ||..:.:|..||...:||.:.::.|..|.:.|.:.|....:..
Zfish   271 LIAAVLKLGNIEFKPESRVNGFDESRVKDKNDLKEMCELLGIEQSVLERAFSFRTVEAKMEKVST 335

  Fly   326 DHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSF 390
            ..|..||.|.:|||||.:|.|||||:::|||.:|   .::|:.| ..|:|||||||||||:.|||
Zfish   336 TLNVAQAYYARDALAKNLYSRLFTWLVNRINESI---KAQTKTR-KKVMGVLDIYGFEIFEDNSF 396

  Fly   391 EQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEAC 455
            |||.||||||||||:||||.|::|||||.||||||||||||||.|||||:|....||:|::||.|
Zfish   397 EQFIINYCNEKLQQIFIELTLREEQEEYIREGIEWTNIEYFNNAIICDLIENNKNGILAMLDEEC 461

  Fly   456 LSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKP----TDKELKHREDFRITHYAGDVIYNINGFIE 516
            |..|.|||:|.|..::...::|.|:.||..|.    ||..|.| ..|||.||||.|:|.:.||::
Zfish   462 LRPGTVTDETFLDKLNTVCAEHQHFESRLSKNSKFLTDHSLPH-NCFRIQHYAGKVLYRVEGFVD 525

  Fly   517 KNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFY 581
            ||.|.||:|..:.::.:....:..::||| ...|...|||.|||..|:.|:..|:..||.|.|.|
Zfish   526 KNNDLLYRDLSQAMYKANHNLIKLLFPEG-NPAKVNLKRPPTAGFQFRASVGTLMKNLLTKNPNY 589

  Fly   582 VRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFR 646
            :|||||||.|::.:|.:..|.||||||||:||:||||||:..||.|:..|.||||:.:.|||:::
Zfish   590 IRCIKPNDKKAAHIFTDSLVCHQVRYLGLMENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWK 654

  Fly   647 AGSDRDGVRVLIEEKKF-AQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVR 710
             |..|:||.||:.:.:. |::..||.:|||||:|||||.||.:|.:.:..:..|:||..|||..|
Zfish   655 -GPAREGVEVLLSDLQVPAEEFAYGRSKIFIRNPRTLFFLEEKRRQCLEDLAALIQKIYRGWKCR 718

  Fly   711 RNFKKMKAAITIVRAY------------------------KAYKLRSYVQELANRLRKAKQMRD- 750
            .:|..:|.:..:|.|:                        :.:|.|..::||.::.|..:.:..
Zfish   719 THFLLLKKSQVVVAAWYRRFAQQKKYQKIRCSALVVQSFIRGWKARKLLRELKHKKRCEEAVTTI 783

  Fly   751 ----YGKSIQWPQPPLAGRKVEA-KLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRP 810
                :|...:|   .|...|.|| ..|.:...|.|  .|....|.|..:|:.:..:..|::....
Zfish   784 SAYWHGTQARW---ELRRLKKEAWNKHAVSVIWAA--WLGTKARRELQKLKHEACSKQAVSVIWA 843

  Fly   811 YW-------------GQARR----------WVG-----DYLANSQENSGYEAYNGSIKNI----- 842
            .|             .:|||          |:|     :|....:.|:|.:.|:.:|:.|
Zfish   844 CWQGTKARRELKRLKEEARRKHAIAVIWAYWLGLKVRREYRKFFRANAGKKIYDFTIQRIIQKYY 908

  Fly   843 ----RNHPA----------------DG------------------------------------ET 851
                :..|:                ||                                    |.
Zfish   909 LGLKKTMPSMSPIDKSWSTCPYGFLDGTHQELRRIFHLWRCKKYRSQFTEEKKATYEEKLAASEL 973

  Fly   852 FQ------------------------------------QVLFSSFVKKFNHFN-KQANRAFIVSD 879
            |:                                    :||.:..|.|.|..| |...|.|:::.
Zfish   974 FKDKKALYPSSVSQPFKGDYVEITKNPKYQKLNSLVEDKVLLADVVSKINRANGKGTPRIFLLTK 1038

  Fly   880 STIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIG 944
            ..:...|   .|...:|.::.:.:|:|:.||...|..  |.....:....:.:.:|. |..||:.
Zfish  1039 KCLVLAD---QKTGQVKASVPLPDLSSVFVSTQNDGF--FALKLREGATSAAKGDYL-LSSDRLI 1097

  Fly   945 EVV------------------------------GIVCKKYHDLTGTELRVNVTTNISCRLDGKAR 979
            |::                              ..||.|:  :.||....|   ::||:.... |
Zfish  1098 EIITKLYCTGAASAERNQIKIDISDEFLVQFKQDKVCVKF--IQGTPKNSN---SVSCKRKNN-R 1156

  Fly   980 IITVEAAS 987
            ::.|...|
Zfish  1157 LLEVSVPS 1164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo31DF	NP_523538.1	MYSc_Myo1	21..677	CDD:276829	344/667 (52%)
		Myosin_TH1	801..977	CDD:461801	49/331 (15%)
myo1b	XP_003199241.2	MYSc_Myo1	26..685	CDD:276829	344/667 (52%)
		IQCD	740..775	CDD:467745	4/34 (12%)
		Myosin_TH1	967..1162	CDD:461801	35/206 (17%)