DRSC/TRiP Functional Genomics Resources

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Protein Alignment RluA-2 and RIB2

DIOPT Version :10

Sequence 1:NP_609411.1 Gene:RluA-2 / 34440 FlyBaseID:FBgn0032256 Length:547 Species:Drosophila melanogaster
Sequence 2:NP_014575.1 Gene:RIB2 / 854088 SGDID:S000005427 Length:591 Species:Saccharomyces cerevisiae


Alignment Length:512 Identity:179/512 - (34%)
Similarity:262/512 - (51%) Gaps:122/512 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 SEEKSETQSKEVLSEK---------RKASSTDDEGHVKKVK------LEANSLKTKRPGFSDERY 122
            |::.:...:||:.|.|         |..:..::...||...      ::.:..|||:   :|..|
Yeast     9 SDDFNNLLNKEIESAKEVKLRKFANRNNNRNENSSKVKDASGFRLRVIQTDGHKTKK---TDPDY 70

  Fly   123 DETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEK 187
            :.|   .:..|||:.|||||:.||.|.||.|.|::||||.|||...|..|.:::..||:.:|.|.
Yeast    71 EVT---IDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKVYLNDEP 132

  Fly   188 VPKDYKIKHNDLLANVVHRHEVPVTSQPIKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILA 252
            ...|..|:..||:.:.|||||.||||:||.||:.|:||:|::||:||||||.||||.||:..:|.
Yeast   133 ANLDTIIRDGDLITHKVHRHEPPVTSKPIDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKMLE 197

  Fly   253 KEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEK 317
            ::... ::...:|||:.||||:...:|...|..:..|::.|:|.||||.||:|.||.||||.::.
Yeast   198 RQLGY-SVHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKP 261

  Fly   318 IDVVSYKI---GVCKVSPK-GKDCKTTFKRIGEVGSDSIVLCKPLTGRMHQIRVHLQFLGYPISN 378
            :..|:.|:   .||::|.: .|..||.|:|:...|..|||.|||||||.||||||||:||:||:|
Yeast   262 VRSVNPKVALNAVCEMSDENAKHAKTVFQRVSYDGQTSIVKCKPLTGRTHQIRVHLQYLGFPIAN 326

  Fly   379 DPLY-NHEVFGPLKGRGG-----DIGGITEEQLISNLISI---HNAENWL--GLEGDQIVSGEIK 432
            ||:| |.:::||..||||     ||        :..|.:|   :.||:|:  ..||:.::.    
Yeast   327 DPIYSNPDIWGPDLGRGGLQNYDDI--------VLKLDAIGKTNPAESWIHPHSEGEYLLG---- 379

  Fly   433 DVAASTSVVEAPSVVQAPINSETEKPVISKNLEPSNDATAQIATQTCYEEPDRSFDSKKTTSDPQ 497
                                                                           .|
Yeast   380 ---------------------------------------------------------------RQ 381

  Fly   498 CSECKIN-YRDPGTKDLIMYLHAWKYKGVG---------WEYETELPEWACNSNIDY 544
            |.||:.. |.||||.||.::|||::|:.:.         |.|.|:.||||...:..|
Yeast   382 CEECEAEMYTDPGTNDLDLWLHAFRYESLERNSDTQKPLWSYRTKYPEWALEPHRRY 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RluA-2NP_609411.1 PseudoU_synth_ScRIB2 202..386 CDD:211331 95/188 (51%)
RIB2NP_014575.1 rluA_subfam 94..406 CDD:161659 145/387 (37%)
Inv-AAD 459..580 CDD:408556
Blue background indicates that the domain is not in the aligned region.

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