Protein Alignment LManII and man2b1

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001072469.1
• Gene: man2b1 / 779924
• XenbaseID: XB-GENE-958698
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 1060
• Identity: 447/1060 - (42%)
• Similarity: 610/1060 - (57%)
• Gaps: 113/1060 - (10%)

  Fly    30 KASQCGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLR 94
            :|..||.|||.......|||||:.|||:||||||||||||||:...||.||||||:||||..||.
 Frog    22 QAEGCGEQSCPQAPDGFLNVHLIPHTHNDVGWLKTVDQYYYGAHNDIQHAGVQYILDSVVSQLLH 86

  Fly    95 DPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWG 159
            ||.|||||||||||::|||:|...|:..|..|||:||||||.|.|||||||.|||.|:|||.:.|
 Frog    87 DPSKRFIYVESAFFWRWWKQQDELVRRDVTRLVEEGRLEFINGGWSMNDEAATHYSSIIDQMTLG 151

  Fly   160 LRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWH 224
            |:.|..|||:||||||.|.|||||||||.|.:|||||:||.||||||||||..|..||..||:|.
 Frog   152 LQFLKSTFGDCGRPRVAWHIDPFGHSREQALLFAQMGYDGFFFGRLDYQDKANREKTKQMEMLWR 216

  Fly   225 GSANLGEE-ADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNVKERIDTFLDFAKTQSQ 288
            .|.::... ||||:|.|.|.|..|||||:|.||:|.||||.....|.|....:..||..|..|:|
 Frog   217 ASDDISPPYADLFTGVLPNGYNPPDGFCWDQLCDDTPIIDDPSVEDYNADVIVQKFLKAATQQAQ 281

  Fly   289 YYRTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITW 353
            .|.:::|::|||.||.|:.|.:::||:|:||:..|.:|.|||.:|:.||||||||:|||.|.:||
 Frog   282 KYLSSHIVMTMGSDFQYENAIMWFKNMDRLIKNVNMQQINGSKVNVFYSTPSCYLQSLHRANLTW 346

  Fly   354 PTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALAPKKPEEFDPH----LT 414
            |.|.|||||||..||.:|||||||||..|.:||..|:|||||.|:.||:..:... .|:    .|
 Frog   347 PMKMDDFFPYADGPHMFWTGYFTSRPAFKGYERLSNNFLQVCNQMEALSGLEARN-GPYGQSSST 410

  Fly   415 FMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQSKDNVKDTSAKYV 479
            .||..:|:.|||||:|||.|:.|..||:.|:|..:.:|.....|:|:.|| .:|:|
 Frog   411 VMRRAMGVAQHHDAVTGTAKQHVNNDYSLRLSEGWDSCQVVISNSLSSLT-GTKEN--------- 465

  Fly   480 FEFKTCALLNITSCPVSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPI 544
              |..|.||||:.|.|:|..:.|.:.|||||..:|...||:||....|::|.....|:.|:.|.:
 Frog   466 --FAFCNLLNISVCHVTETANNFKVYLYNPLGRSVTWTVRLPVNGHAYKVIGPNDETVPSEVVDV 528

  Fly   545 PQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTE----GNTRSKALPKRTSSVTVIG 605
            ......::.:...|:.|::|.. .|||:|:.::.|.||...:    ...|.|..|.:      |.
 Frog   529 SDFTKALRFQQGGAERELIFQG-QIPAVGFSSFTVGKLSLPDRFVIKGKRGKKQPDK------IQ 586

  Fly   606 NSHIQLGFD-TNGFLSEVTADGLTRLVS----QEFLFYEGAVGNNAEFLNRSSGAYIFRPNENKI 665
            |.:.::.|| ..|.:|.:  ..|.:.:|    |.|.:|..:|||  |..::.|||||||||.:..
 Frog   587 NQYYRVDFDPETGLISGI--HNLEKKISLPLKQSFYWYNASVGN--EESSQPSGAYIFRPNNSDS 647

  Fly   666 HFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPIDDGIGKEVITRFN 730
            ...:..|...:.:..||.||||.|:.|.|||||:|....|.|.||.|||:||.|..|||||:...
 Frog   648 VPVSQHVRSYLVQNSLVQEVHQNFSSWCSQVVRLYRDQRYIELEWTVGPVPIGDEWGKEVISLIE 712

  Fly   731 SDIASDGIFRTDSNGREMIKRKINHRDTWSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQ 795
            :::.:||:|.||||||:::||:.:.|:||.:...|.:||||||:.::|.::....::.:||||:|
 Frog   713 TNLKTDGVFYTDSNGRQILKRRRDSRETWKLNQTEPIAGNYYPVNSRIYIKGKNTQVTVLTDRSQ 777

  Fly   796 GGSSLKDGSLELMVHRRLLKDDAFGVGEALNETE-YGDGLIARGKHHLFFGKSTDREGVSLKGIE 859
            ||||::|||||||||||||:||..||||.|.|.. .|:|::.||:|.|....:.:....     .
 Frog   778 GGSSIRDGSLELMVHRRLLRDDYRGVGEPLLENGLLGEGIVVRGRHLLLLDHADEAADT-----H 837

  Fly   860 RLTQLEKLLPTWKFFSNMEDYSADEWQTAFTNIFSGISLVLPKPVHLLTLEPWHENQLLVRFEHI 924
            |...|::.:......|:.:.....:..|. ...||.::..||:..||||......:::|:|.||.
 Frog   838 RTLALQQYMSPQVVLSSGDGIPYSQSGTP-KRKFSALNGELPQNGHLLTFAMHAADKILLRLEHP 901

  Fly   925 MENGEDASYSQPVQFNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQ 989
            .::.|..:.|||:..|:..:.|:..:....||||..|......:|||:.              ::
 Frog   902 FQSQESKNNSQPITINLNTLFSSVSLSNFEETTLGANMEKSRLKRLQWR--------------TR 952

  Fly   990 PAESVHLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGPYNSFKS 1054
            ....:.:.|...|::
 Frog   953 TGSPLQMDSPRAPVV-------------------------------------------------- 967

  Fly  1055 DSSNQEYIIELSPMEIRTFI 1074
            |.||    |.|||||||||:
 Frog   968 DPSN----ITLSPMEIRTFL 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	386/789 (49%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	168/276 (61%)
man2b1	NP_001072469.1	PLN02701	39..987	CDD:178304	441/1043 (42%)
		GH38N_AMII_LAM_like	39..317	CDD:212121	168/277 (61%)