Protein Alignment LManII and man2a1

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001103497.3
• Gene: man2a1 / 560219
• ZFINID: ZDB-GENE-060526-31
• Length: 1150
• Species: Danio rerio
• Alignment Length: 861
• Identity: 240/861 - (27%)
• Similarity: 380/861 - (44%)
• Gaps: 130/861 - (15%)

  Fly    47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKW 111
            |.|.:|.|:|:|.|||||.|.||        :...|:|::::|..|..|..::.|:.|.::|.||
Zfish   164 LQVFVVPHSHNDPGWLKTFDDYY--------RDQTQHILNNMVVKLHEDSRRKMIWSEISYFAKW 220

  Fly   112 WKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVG 176
            |.....:.|:||:.|||.|:||...|.|.|.|||..||.::|||...|.:.|....|.  :|:.|
Zfish   221 WDSIDGQKQDAVRRLVENGQLEVATGGWVMPDEANAHYFAMIDQLVEGHQWLERNLGV--KPKTG 283

  Fly   177 WQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFSGAL- 240
            |.:|||||:...|.:....|...|...|:.|..|......|..|..|..:.:.....|:....:
Zfish   284 WAVDPFGHTATQAYLLKLAGLSNMLIQRVHYSVKKHFSSQKTLEFFWRQNWDQDSSTDILCHMMP 348

  Fly   241 YNNYQAPDGFCFDILCNDAPII----DGKHSP----------------DNNVKERIDTFLDFAKT 285
            :.:|..|.      .|...|.|    |.|..|                ||||:||..|.||..:.
Zfish   349 FYSYDVPH------TCGPDPKICCQFDFKRLPGGRISCPWRIPPQAITDNNVQERAQTLLDQYRK 407

  Fly   286 QSQYYRTNNIIVTMGGDFTYQAAQVY---YKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLH 347
            :|:.:||..::..:|.||.|..|..:   ::|..||..|.|....  .::...:.|.|.|.::|.
Zfish   408 KSKLFRTKVLLAPLGDDFRYTEAVEWDQQFENYQKLFDYMNSHPE--LHVKAQFGTISDYFQALR 470

  Fly   348 DA-----------GITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSAL 401
            .:           .:..|..|.|||.||.....||:|||||||..||.:|....:|:..:.|.:|
Zfish   471 KSTGMDPVGMNVGHLALPVVSGDFFTYADRDDHYWSGYFTSRPFYKRMDRMLESYLRAAEVLYSL 535

  Fly   402 APK------KPEEFDPH-----LTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGAT 455
            ...      :|.::...     ||..|..||:.||||||.||.|:.|.:||..|:..:.......
Zfish   536 TLANIQKYGQPSDYPAGENYKLLTEARRNLGLFQHHDAIAGTGKDWVVVDYGTRLFHSILNVKRV 600

  Fly   456 TRNALNQLTVQSKDNVKDTSAKYVFEFKTCALLNITSCPVSEANDRF-------------ALTLY 507
            ..::.:.|.::.|....:..:|        |.|.:..  |.::.|..             .|.:.
Zfish   601 IVSSAHWLVLKDKQTYHNDPSK--------AFLQMDD--VQQSQDALPRKNVLEVHGKPRLLVVS 655

  Fly   508 NPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPAL 572
            |||.......|.:.|...|.|::...|..:.:|   :..|..|..|..:.. :::.|:|...| |
Zfish   656 NPLEQARTSMVTVYVNTPNVRVLSALGQVVRAQ---VSAVWKDASHATADV-FQLSFVAHAAP-L 715

  Fly   573 GYRTYYV-----EKLDST------EGNTRS-------KALPKRTSSVTVIGNSHIQLGFD-TNGF 618
            |...|.:     .:.|::      ||...|       :...:...:..||.|.|::|... ..|.
Zfish   716 GLSVYQLIEVMEPRTDASKYMFLQEGRQLSDSKLEHFRQFYQDDGAPVVIENPHLRLSISGATGL 780

  Fly   619 LSE--VTADGLTRLVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPN-ENKIHFATDQVEIEVYKGD 680
            |.:  :..|.....:..||::| |...:..:     ||||:|.|: |..|:..:....|.|.||.
Zfish   781 LEKMMLKEDESEHQMKVEFVWY-GTTSSKDK-----SGAYLFLPDKEATIYSPSQPPVIRVTKGT 839

  Fly   681 LVHEVHQKFNDWISQVVRVYNKDSY-AEFEWLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSN 744
            |..||...|.. |:..:|:||.... .:...:...:.|.....:|:..|..||:.|...|.||.|
Zfish   840 LFSEVTTTFAH-ITHTLRLYNTQGVEGQSVEICNTVDIRGETNREIAMRITSDLNSKDRFFTDLN 903

  Fly   745 GREMIKRKINHRDTWSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMV 809
            |.::..||.      ..|:  .:..|:||:|:.:.::|.:||:::||.::.|.:|||.|.||:::
Zfish   904 GYQVQPRKT------MAKL--PLQANFYPMTSMLYLQDSSARLSLLTAQSLGAASLKSGQLEVIM 960

  Fly   810 HRRLLKDDAFGVGEAL 825
            .|||.:||..|:|:.:
Zfish   961 DRRLNQDDNRGLGQGV 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	239/857 (28%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	95/299 (32%)
man2a1	NP_001103497.3	None