Protein Alignment LManII and man2b1

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: XP_005169420.1
• Gene: man2b1 / 541519
• ZFINID: ZDB-GENE-050327-52
• Length: 984
• Species: Danio rerio
• Alignment Length: 1061
• Identity: 473/1061 - (44%)
• Similarity: 629/1061 - (59%)
• Gaps: 127/1061 - (11%)

  Fly    32 SQCGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDP 96
            |.|||:||..|||:|||||||.|||||||||||||||:||....||.||||||:|||::.|.:||
Zfish    29 SICGYKSCPATKPSMLNVHLVPHTHDDVGWLKTVDQYFYGDRNNIQHAGVQYILDSVIDQLQKDP 93

  Fly    97 EKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQFSWGLR 161
            .:||||||:|||::||::|....:..|..||.:||||||.|.|.|:|||||||.:||||.:.|||
Zfish    94 ARRFIYVETAFFYRWWRQQNQNTRRIVTQLVNEGRLEFINGGWCMSDEATTHYSAVIDQMTLGLR 158

  Fly   162 LLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGS 226
            .|||||||||||||.|.||||||:||.||:|||||:||.|||||||||||.|:.||..||:|..|
Zfish   159 FLNDTFGECGRPRVAWHIDPFGHAREHASIFAQMGYDGFFFGRLDYQDKDRRMKTKEMEMLWRAS 223

  Fly   227 ANLGEE-ADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNVKERIDTFLDFAKTQSQYY 290
            .:|... ||||:|.|.|.|..|:|||:|..|:||||.|.....|.||.|.:..||:.:..|:.||
Zfish   224 ESLTPPIADLFTGVLPNGYNPPEGFCWDQSCDDAPIRDDPDLEDYNVDEIVQKFLNASHKQADYY 288

  Fly   291 RTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITWPT 355
            :||:||:|||.||.|:.|.::|||:||||:|.|..||.||.:|:|||||||||:.|:.|..|||.
Zfish   289 KTNHIIMTMGSDFQYENANLWYKNMDKLIKYVNALQAKGSKLNVLYSTPSCYLQELNLANFTWPM 353

  Fly   356 KSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSAL-------APKKPEEFDPHL 413
            |:|||||||.|.|.:|||||||||.||.:||..|..||.|.||..|       .|....:.|.
Zfish   354 KTDDFFPYADDAHDFWTGYFTSRPALKLYERLSNSRLQTCNQLEVLGGPTSTSGPFGEGDSDT-- 416

  Fly   414 TFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQSKDNVKDTSAKY 478
              ||..:|:.|||||::||||:.||.|||:|::..:..|.....|:|..|:        .:.|..
Zfish   417 --MRRAMGVAQHHDAVSGTEKQHVANDYARRLATGWAHCEVLVSNSLAVLS--------GSEAPR 471

  Fly   479 VFEFKTCALLNITSCPVSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVP 543
            ||    |..|||:.||::|::.:|::.:||||..||...||:||..|.|.:.|..|..::|:.:|
Zfish   472 VF----CENLNISVCPLTESSHKFSMNVYNPLGRTVRWPVRLPVNGSVYNVTDANGKAVDSEVIP 532

  Fly   544 IPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTEGNTRSK-ALPKRTSSVTVIGNS 607
            :.:...:::.....||.|:|| ....|.|||.||.:..:......:||| |:|      :.|.|.
Zfish   533 LSKSRKEVRQNRGFAKSELVF-QVEAPPLGYSTYIISMVQDQPPVSRSKNAVP------SSIQNK 590

  Fly   608 HIQLGFD-TNGFLSEVT--ADGLTRLVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPNENKIHFAT 669
            .:::.|| |.|.||.:|  ....|..::|.|.:|..:.|||.| .::.|||||||||.:.....:
Zfish   591 FLKVTFDSTTGLLSSLTNLETQQTIRLTQNFFWYNASAGNNKE-SHQPSGAYIFRPNSSDPFIIS 654

  Fly   670 DQVEIE---VYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPIDDGIGKEVITRFNS 731
            ...||:   :|..  |.||.|:|:.|:|||||:|......|.||.|||:|::||:|||||||.::
Zfish   655 KTAEIQAVSLYNS--VQEVTQRFSPWVSQVVRLYEDRRELELEWTVGPVPVEDGLGKEVITRLDT 717

  Fly   732 DIASDGIFRTDSNGREMIKRKINHRDTWSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQG 796
            ||.|.|.|.|||||||:::|:.::|.||.:|..|.:|||||||.::..::||..::.::|||:||
Zfish   718 DIQSSGYFYTDSNGREVLERRKDYRPTWDLKQTEPIAGNYYPINSRAYIKDDKRQLTVVTDRSQG 782

  Fly   797 GSSLKDGSLELMVHRRLLKDDAFGVGEALNET-EYGDGLIARGKHHLFFGKSTDREGVSLKGIER 860
            .||:.:||||:|:|||||.||..||||.|:|. |:..||:|||:  |....|.......|.  ..
Zfish   783 ASSIYNGSLEIMLHRRLLYDDFRGVGEPLSEPGEFAHGLVARGR--LLLTLSPPEAAADLH--RP 843

  Fly   861 LTQLEKLLPTWKFFSNMEDYSADEWQTAFTNI-FSGISLVLPKPVHLLTLEPWHENQLLVRFEHI 924
            |.|...|.|...|        .|...:..|.: |||:...||..|||||:..|.::.:|||.||.
Zfish   844 LAQSMVLQPLLSF--------QDGAPSPGTKLEFSGLQAALPPAVHLLTVSQWDQDSVLVRLEHQ 900

  Fly   925 MENGEDASYSQPVQFNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQ 989
            .:..|..::||||..|::.:.|...|.|..|.:|..|.|.::..||.         :||
Zfish   901 YQAKESKTHSQPVTVNLQKLFSTLQVLGASEMSLGANQWKEDMIRLH---------WNT------ 950

  Fly   990 PAESVHLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGPYNSFKS 1054
                      ||         :|||                      ...|...|.|
Zfish   951 ----------EK---------DALP----------------------PTARDPSSWE-------- 966

  Fly  1055 DSSNQEYIIELSPMEIRTFIV 1075
                    :.|.|||||||::
Zfish   967 --------VTLKPMEIRTFLL 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	394/790 (50%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	172/276 (62%)
man2b1	XP_005169420.1	PLN02701	44..982	CDD:178304	463/1046 (44%)
		GH38N_AMII_LAM_like	44..322	CDD:212121	172/277 (62%)