Protein Alignment LManII and man2a2

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001006777.1
• Gene: man2a2 / 448465
• XenbaseID: XB-GENE-981388
• Length: 909
• Species: Xenopus tropicalis
• Alignment Length: 796
• Identity: 227/796 - (28%)
• Similarity: 345/796 - (43%)
• Gaps: 154/796 - (19%)

  Fly    47 LNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKW 111
            |.|.:|.|:|:|.||:||.|:|||..        .|:|::::|..|..||.::||:.|.:||.||
 Frog   166 LQVFVVPHSHNDPGWIKTFDKYYYDQ--------TQHILNNMVVKLHEDPRRKFIWSEISFFSKW 222

  Fly   112 WKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQF----SWGLRLLNDTFGECGR 172
            |.....:.:.||:.||..|:||...|.|.|.|||.|||.::|||.    .|..:.|:.|
 Frog   223 WDNINSQKRAAVRRLVASGQLEMTTGGWVMPDEANTHYFAMIDQMIEGHQWLKKNLDAT------ 281

  Fly   173 PRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFS 237
            ||.||.:||||||..|..:..:.....|...|:.|..|.....|::.|.:|..:.:.....|:|.
 Frog   282 PRSGWAVDPFGHSSTMPYILRRSNLTSMLIQRVHYSIKKHFAATQSLEFMWRQTWDPDSSTDIFC 346

  Fly   238 GAL-YNNYQAPDGFCFDILCNDAPII----DGKHSP----------------DNNVKERIDTFLD 281
            ..: :.:|..|.      .|...|.|    |.:..|                |:||.||.:..||
 Frog   347 HMMPFYSYDVPH------TCGPDPKICCQFDFRRLPGGRINCPWKVPPRAITDSNVAERANILLD 405

  Fly   282 FAKTQSQYYRTNNIIVTMGGDFTYQAAQVY---YKNLDKLIRYGNERQANGSNINLLYSTPSCYL 343
            ..|.:|:.||:..::|.:|.||.|...|.:   :.|..||..|.|....  .::...:.|.|.|.
 Frog   406 QYKKKSKLYRSKVVLVPLGDDFRYDKIQEWDAQFLNYQKLFDYMNSHPE--LHVQAQFGTLSDYF 468

  Fly   344 KSLHD-----AGI---TWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSA 400
            .:|:.     .||   .:|..|.|||.||.....|||||:||||..|..:|.....|:..:.|.:
 Frog   469 DALYKRMGVVPGIKPPDFPVVSGDFFSYADREDHYWTGYYTSRPFYKSMDRVLESHLRGAEILYS 533

  Fly   401 LA----------PKKPEEFDPHLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGAT 455
            ||          .|.|......||..|..||:.|||||||||.||.|.:||..|:..:.......
 Frog   534 LAINHARKAGTESKYPLSDYALLTDARRNLGLFQHHDAITGTAKEAVVIDYGVRLLHSLMNLKRI 598

  Fly   456 TRNALNQLTVQSKDNVKDTSAKYVFE-----FKT------------CALLNITSCPVSEANDRFA 503
            ..||.:.|.|..|:       ||.::     |.|            ..::.:|:.|      |:
 Frog   599 IINAAHYLVVADKE-------KYHYDHSVPFFSTDESRLTQESLPEKTVIKLTASP------RY- 649

  Fly   504 LTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATN 568
            :.::||:.......|.:.|...|.|::...|..:.:|..|:.|.:.|:    :...|::.|.| .
 Frog   650 VVVFNPVEQNRLCVVSLLVNTYNVRVLTEDGQPVAAQLSPVWQSVTDM----NPDVYQVSFTA-R 709

  Fly   569 IPALGYRTYYVEKLDSTEGNTRSK----------------ALPKRTSSVTV----IGNSHIQLGF 613
            :|:||...:.:.....|....:|.                ..|.:.:..:.    |.|.::|:.|
 Frog   710 LPSLGLSIFQLHASIDTHTTLKSNVRVHLHGRELSIKKQDVFPVKVAESSTDDFHIENQYMQVWF 774

  Fly   614 D-TNGFLSEVTADG--LTRLVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPN-ENKIHFATDQVEI 674
            . |.|.|..:...|  ..:.::.:||.|......:      .||||:|.|: |.|.:...|...:
 Frog   775 SGTTGLLKSIKRAGEEQEQKINMQFLIYGTRTSKD------KSGAYLFLPDGEAKPYTPKDPPVV 833

  Fly   675 EVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGP----------IPIDDGIGKEVITRF 729
            :|.:|....||..::.. :.||:|:||         |.|.          |.|.|.:.||:..|.
 Frog   834 KVTEGPFYSEVTCQYQH-VQQVMRLYN---------LPGTEGLSLDISSLIDIRDHVNKEIAMRL 888

  Fly   730 NSDIASDGIFRTDSNG 745
            ::||.|:.||.||.||
 Frog   889 STDIQSEDIFFTDLNG 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	227/796 (29%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	98/303 (32%)
man2a2	NP_001006777.1	PLN02701	128..>906	CDD:178304	227/796 (29%)