Protein Alignment LManII and LManVI

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Alignment Length: 1107
• Identity: 486/1107 - (43%)
• Similarity: 670/1107 - (60%)
• Gaps: 149/1107 - (13%)

  Fly     9 LVFFCALGCLIHDADLRSIQPKASQCGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSE 73
            :|.|.||..:       |::|....|||::|..||.||:|:|:|.|:|||||||||||||:||..
  Fly     7 IVLFVALLAI-------SVRPSEEACGYEACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYGHR 64

  Fly    74 TKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGA 138
            :.||.||||||||:|:..|::||.:|||.||::||.|||.||....::.|:.||.:|||||.|||
  Fly    65 SNIQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAKWWAEQSETAKQVVRKLVNEGRLEFTGGA 129

  Fly   139 WSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFG 203
            |||||||..:||||||||:.||:.|:||||.|.|||:||||||||||||.||:|||||:||.||.
  Fly   130 WSMNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPRIGWQIDPFGHSREQASIFAQMGYDGEFFA 194

  Fly   204 RLDYQDKDERLMTKNAEMIWHGSANLGEEADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSP 268
            |:|::||::|:.....||||..|.:|..: ::|:|.||.:|.||.|:|||:.|.|.||||.| |.
  Fly   195 RMDHRDKNDRIDNLGMEMIWDASDSLSND-EIFTGLLYRHYSAPPGYCFDVHCGDDPIIDTK-SY 257

  Fly   269 DNNVKERIDTFLDFAKTQSQYYRTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNIN 333
            |||||.|:|.||.:..:.:|:||:|:|::.||.||.|:.|||.:||:||||:|.|||||.||..|
  Fly   258 DNNVKSRVDDFLSYVTSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNERQAEGSTFN 322

  Fly   334 LLYSTPSCYLKSLHDAGITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQL 398
            |.||||:|||.|||:...|||.|:.|||||.||.::|||||||||||.|||||||||.|||.|||
  Fly   323 LFYSTPACYLNSLHEGLQTWPNKTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHILQVAKQL 387

  Fly   399 SALAPKKPEEFDPHLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQL 463
            |..|....::....|.::||.:|:||||||||||||:.|:.||.:.:..|......|.|:.|.:|
  Fly   388 SVFAELNTKQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAILGGVNTARDGLRKL 452

  Fly   464 TVQSKDNVKDTSAKYVFEFKTCALLNITSCPVSEAN-DRFALTLYNPLAHTVNEYVRIPVPYSNY 527
            |     |:.:.      ||::|..|||:.|..::.: |...:|||||||||..:|||:||...||
  Fly   453 T-----NLPNG------EFESCLQLNISECAFTKDDADNVVVTLYNPLAHTSTQYVRVPVKNENY 506

  Fly   528 RIIDNKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTE-----G 587
            .:.|.||..:.|:.||:...::.::.||:..::|:||.| ::..:.  .||::|:.|.|     .
  Fly   507 EVTDEKGRVVASEVVPVAWQVLALEFRNNDTQHELVFKA-SVDKIA--NYYIKKVASQETKNVAA 568

  Fly   588 NTRSK----------ALPKRTSSV----------------TVIGNSHIQLGFDT-NGFLSEVTAD 625
            :|:||          .:|||...|                ||:..|.::|..|. .|.|..|..:
  Fly   569 HTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQTSQVKLVIDNKTGLLKTVEMN 633

  Fly   626 GLTRLVSQEFLFYEGAVGNNAEFLNRSSGAYIFRPNENKIHFAT-----DQVEIEVYKGDLVHEV 685
            |::..:.|.:..|.          ...||||:||    :.|.|.     :.||..||.|.||.||
  Fly   634 GVSENIDQSYGVYR----------TYDSGAYVFR----QYHQADFIVQYEGVEFTVYDGALVKEV 684

  Fly   686 HQKFNDWISQVVRVYNKDSYAEFEWLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIK 750
            ||:|:::||||:|:|...:..|.||.||||..::..|:||:..|||.|||||:..||||||||||
  Fly   685 HQQFSEYISQVIRIYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASDGVSYTDSNGREMIK 749

  Fly   751 RKINHRDTWSVKIN-EAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLL 814
            |..:.|:|::..:: :..|.||||:|::|.::|...|:|:|.||||||:|:.:|.||||:||||:
  Fly   750 RVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQLELMLHRRLV 814

  Fly   815 KDDAFGVGEALNETEYGDGLIARGKHHLFFGKSTDREGVSLKGIERLTQLEKLLPTWKFFS-NME 878
            :||.:||||||||.:||..:|||||.:|....|.:....     ||..:.|..||.||||| |..
  Fly   815 RDDGYGVGEALNEEKYGQPMIARGKVYLILSPSDESTAA-----EREAEKEIHLPFWKFFSKNTG 874

  Fly   879 DYSADEWQTAFTNIFSGISLVLPKPVHLLTLEPWHENQLLVRFEHIMENGEDASYSQPVQFNVKN 943
            ..:|........|.|       ||.||||||||::::::|:|.|:.:::.|    .|.|.||::.
  Fly   875 STTAAAKSVPSFNDF-------PKSVHLLTLEPFNDDEVLLRVENFLDHTE----GQVVSFNIRP 928

  Fly   944 VLSAFDVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQPAESVHLLSAEKPMLGVKY 1008
            :....:...|||||||||..|.:.:|.:|..|         ::..:|....:..||.|| |..:.
  Fly   929 IFDYLNGVEIRETTLDGNLPLSDMKRFKFHHD---------SSGQKPDAVEYFTSAHKP-LAAEQ 983

  Fly  1009 ADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGPYNSFKSDSSNQEYIIELSPMEIRTF 1073
            :.||                                              .|:.:.|.||:||||
  Fly   984 SQEA----------------------------------------------SEFSVTLHPMQIRTF 1002

  Fly  1074 IV 1075
            |:
  Fly  1003 II 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	395/814 (49%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	164/275 (60%)
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	164/275 (60%)
		PLN02701	40..898	CDD:178304	429/899 (48%)