Protein Alignment LManII and LManV

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Alignment Length: 1083
• Identity: 483/1083 - (44%)
• Similarity: 671/1083 - (61%)
• Gaps: 129/1083 - (11%)

  Fly    15 LGCLIHDADLRSIQPKASQ--CGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQ 77
            ||.::..|.| ::|.|::|  |||:|||.||.||:|:|||.|:||||||||||||||||....||
  Fly     4 LGIVLCVAFL-ALQAKSAQAVCGYESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYYGHRNNIQ 67

  Fly    78 KAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMN 142
            .||||||||:|:..|:::|::|||.||::||.|||.||...::..|||||.:|||:||.||||||
  Fly    68 HAGVQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFINGAWSMN 132

  Fly   143 DEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDY 207
            |||..:||||||||:.||:.|:||||.||||||||||||||||||.||::|||||||.||.|:|:
  Fly   133 DEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGFDGEFFSRMDH 197

  Fly   208 QDKDERLMTKNAEMIWHGSANLGEEADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNV 272
            .||..|:.....||||..|.:| .:..||:|.||..|....|||||:.|:|.|||| ..|.||||
  Fly   198 NDKGRRMNDLALEMIWDASESL-SQVKLFTGLLYTFYWDTPGFCFDVHCSDDPIID-SDSYDNNV 260

  Fly   273 KERIDTFLDFAKTQSQYYRTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYS 337
            |.|:|.|:.:|...::.:|||:|::.|||||.|:.|:|.|||:||||:|.||||::||..|::||
  Fly   261 KSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQSSGSKYNIIYS 325

  Fly   338 TPSCYLKSLHDAGITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALA 402
            ||:|||.|:|.:..::|.|:.|||||.||.:::||||:|||||.|||||||||.|||.|||||.|
  Fly   326 TPTCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHILQVAKQLSAFA 390

  Fly   403 PKKPEEFDPHLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQS 467
            .....:....|.::||.:|:||||||||||||:.|:.||.:.:..|......|..:||.:||
  Fly   391 ELSSTQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAIVGGVKTAGDALRKLT--- 452

  Fly   468 KDNVKDTSAKYVFEFKTCALLNITSCP-VSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIID 531
              |:.:.      ||::|..|||:.|. ..:..|...:||||.||||..:|||:||...||::.|
  Fly   453 --NLPNG------EFESCLQLNISECAFTKDGADNVVVTLYNALAHTTKQYVRVPVKNENYQVTD 509

  Fly   532 NKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTEGNTRSKAL-- 594
            .||..:.|:.||:|..::.::.|:|..::|:||.| ::..:.  .||::|:||.|.:...:.:
  Fly   510 EKGRVVASEIVPVPAEVLALEFRDSDTQHELVFKA-SVDKIA--NYYIKKVDSKESSNGVRVISQ 571

  Fly   595 PKRTSSV-----TVIGNSHIQLGFDT-NGFLSEVTADGLTRLVSQEFLFYEGAVGNNAEFLNRSS 653
            ||..:..     |::..|.|:|..|. .|.|..|..:|::..:.|.:..|.          ...|
  Fly   572 PKANAETYDDEETIVQTSLIKLVLDNKTGLLKRVEMNGVSENIEQSYGLYR----------TYDS 626

  Fly   654 GAYIFRP-NENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPI 717
            |||:||. |:.......|.||..||.|.||.||||:|:::||||:|:.....|.||||||||||:
  Fly   627 GAYVFRQYNQGDFVIQEDGVEFTVYDGALVKEVHQRFSEYISQVIRISEDKPYVEFEWLVGPIPV 691

  Fly   718 DDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKIN-EAVAGNYYPITTKIDVE 781
            ::..|.||:|.|:|:|||:|:|.|||||||:|:|:.:.|:.::.::. :..:|||||||::|.::
  Fly   692 EEEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKREDFTPELAVQPTSGNYYPITSRIALQ 756

  Fly   782 DDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHHLFFGK 846
            |...|:|||.||||||:|:|||.:|||:||||::||.:||||||||.:||..||||||..|....
  Fly   757 DSNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEEKYGQPLIARGKVFLILNA 821

  Fly   847 STDREGVSLKGIERLTQLEKLLPTWKFFSNM--EDYSADEWQTAFTNIFSGISLVLPKPVHLLTL 909
            :.:....     ||..:.|..||.|||||..  ...:|.:...:|.:        .||.||||||
  Fly   822 ADESTSA-----EREAEKEFHLPLWKFFSKNTGSTTAAAKSVPSFDD--------FPKSVHLLTL 873

  Fly   910 EPWHENQLLVRFEHIMENGEDASYSQPVQFNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAP 974
            ||::::::|:|    :||.:|....:.|.||::.:....:...|||||||||..|.:.::.:|
  Fly   874 EPFNDDEILLR----VENFKDHIEGKVVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKQFKF-- 932

  Fly   975 DPEEAAFNTYATFSQPAESVHLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEG 1039
                                |.                                         ||
  Fly   933 --------------------HA-----------------------------------------EG 936

  Fly  1040 RSSKSTEGPY--NSFKSDSSNQ-----EYIIELSPMEIRTFIV 1075
            ...:.:|..|  :|.|..|:||     |:.:.|.||:|||||:
  Fly   937 SGIRGSEPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTFII 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	391/786 (50%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	167/275 (61%)
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	167/275 (61%)
		PLN02701	39..873	CDD:178304	423/872 (49%)