Protein Alignment LManII and alpha-Man-IIa

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: XP_318477.5
• Gene: alpha-Man-IIa / 1278838
• VectorBaseID: AGAMI1_006571
• Length: 1139
• Species: Anopheles gambiae
• Alignment Length: 1043
• Identity: 282/1043 - (27%)
• Similarity: 436/1043 - (41%)
• Gaps: 210/1043 - (20%)

  Fly    40 HPTKPN---MLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQKAGVQYIIDSVVEALLRDPEKRFI 101
            ||::.|   .|:|.:|.|:|:|.||::|.|:||        :...:.|..:::..|..:...|||
Mosquito   155 HPSEWNSHHKLHVFVVPHSHNDPGWIQTFDEYY--------ERSTKNIFANMLRHLDENAGMRFI 211

  Fly   102 YVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMNDEATTHYQSVIDQF----SWGLRL 162
            :.|.::|.:|:.:...:.::.||.||::.:|||:.|.|.|.|||.:|:.|::.|.    :|....
Mosquito   212 WAEISYFAQWYDKLAAEQKDIVKRLVKKRQLEFVTGGWVMPDEANSHWYSMLLQLTEGQTWLQTR 276

  Fly   163 LNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDYQDKDERLMTKNAEMIWHGSA 227
            ||.|      |...|.|||||.|..|..:..|.||:.:...|..|..|....:.|..|..|....
Mosquito   277 LNVT------PVSSWSIDPFGQSATMPYILKQSGFENLLIQRTHYIVKKNLALKKQLEFRWRQLW 335

  Fly   228 NLGEEADLFSGAL-YNNYQAPDGFCFDILCNDAPII----DGKHSP----------------DNN 271
            :...:.|||:..: :.:|..|.      .|...|.|    |.|..|                |.|
Mosquito   336 DTRGDTDLFTHMMPFYSYDVPH------TCGPDPKICCQFDFKRLPSMGLSCPWNVPPKPITDQN 394

  Fly   272 VKERIDTFLDFAKTQSQYYRTNNIIVTMGGDFTY------QAAQVYYKNLDKLIRYGNERQANGS 330
            |.||.:..:|..:.:|..|||.|:::.:|.||.|      :|.:|   |.::|..|.|...:  .
Mosquito   395 VAERAEMIVDQWRKKSVLYRTRNVLIPLGDDFRYTTSSEWEAQRV---NFEQLFNYINNEPS--L 454

  Fly   331 NINLLYSTPSCYLKSLHD----AGI-TWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNH 390
            |:...::|...|..::..    :|: .:|:.:.|||.||.....||:|||||||..||.:|...|
Mosquito   455 NVEAKFATLQDYFDAVRSTSGASGMEQFPSLTGDFFTYADVNQDYWSGYFTSRPYHKRQDRILLH 519

  Fly   391 FLQVCKQLSALAPKKPE-EFDP---HLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRA 451
            :::..:.|.|....:|: ::.|   .|.:.|..|.:.||||.||||.|:.|..|||||||.|...
Mosquito   520 YIRSAEMLHAWNVWEPDSDWKPLAERLEYARRQLSLFQHHDGITGTAKDHVMEDYAKRMSRAIED 584

  Fly   452 CGATTRNALNQL----------------------TVQSKDNVKDTSAKYVFEFKTCALLNITSCP 494
            |....:.::.:|                      ||...|||:.|..
Mosquito   585 CKFVMQQSVYRLLTKPSVYQPDPAFMYLSIDDSRTVNGSDNVRPTII------------------ 631

  Fly   495 VSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPI------------PQV 547
            :.|......:.|:|.|.:|.:|.|...|......::|..|.|:.||..|:            ||
Mosquito   632 LGEELPSKQVVLHNSLPYTRSEVVEFYVASPFVTVLDGNGGTVPSQIAPVWSWHTRPDSISQPQ- 695

  Fly   548 LIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTE---GNTRSKALPKRTSSVTV------ 603
                   .|..||.::|.| |:|.||...|.:...:|.|   |.|.:|.:....|..||
Mosquito   696 -------PSNTKYRLLFRA-NVPPLGLSVYTINSKNSAEESLGVTYTKVIILSKSPFTVNLAAGY 752

  Fly   604 ------IGNSHIQLGFDTNGFLSEV-TADGL-----------TRLVSQEFLFYEGAVGNNAEFLN 650
                  ...:.:.|.|:..|..|.. |:.||           |..|..||..|      ..:..:
Mosquito   753 PEDIDHASPTEMSLRFEEGGSTSAAFTSKGLLKSLTIENNQATVPVHLEFYRY------GMQLSS 811

  Fly   651 RSSGAYIFRPNENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPI 715
            ..||||:|.|..|......||..:.|.||.|...:.......:.|.:.   :|...|...||
Mosquito   812 GKSGAYLFHPAGNATLMTYDQPIVLVMKGPLETSITAGLPFAVHQTIL---RDDSVEIRNLV--- 870

  Fly   716 PIDDGIGK----EVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKINEAVAGNYYPITT 776
                .||:    |::.|..::|.|...|.||.||.::||||...:        ..:..||||:.:
Mosquito   871 ----DIGQRDNTEIVMRLQTNINSGATFYTDLNGMQIIKRKRFQK--------LPIQANYYPVPS 923

  Fly   777 KIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHH 841
            .:.:|||..|:.:|..:..|||||..|.:|:|..|||.:||..|:|:.:.     |.|...   |
Mosquito   924 TMFIEDDNYRLTLLGGQPLGGSSLSSGEMEIMQDRRLTRDDDRGLGQGVQ-----DNLPVL---H 980

  Fly   842 LFFGKSTDREGVSLKGIERLT---------QLEKLL-PTWKFFSNMEDYSA---DEWQTAFTNIF 893
            ||......||..:....:..|         ||:.|| |..|...|..|::.   :.:.:....:.
Mosquito   981 LFRLVLESRESCTKPDPDYPTGFLTLPAHAQLQSLLHPLDKLIYNENDWTGVQMESFGSRHEPLE 1045

  Fly   894 SGISLVLPKP---VHLLTLEPWHENQLLVRFEHIMENGEDASYSQPVQFNVKNVLSAFDVEGIRE 955
            .|:.:|..:.   ||...........|:|...:..:.|.:|:...  ..|:|.:|:..|...|..
Mosquito  1046 QGLEVVAIRQLSHVHFGRTSGASPVGLIVHRTNFEDCGSEANMEG--MLNIKKLLNLDDEHDIYS 1108

  Fly   956 TTL 958
            ..|
Mosquito  1109 ARL 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	248/880 (28%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	89/306 (29%)
alpha-Man-IIa	XP_318477.5	None