Protein Alignment LManII and man2b2

DIOPT Version :10

• Sequence 1: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001106515.1
• Gene: man2b2 / 100127706
• XenbaseID: XB-GENE-1006292
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1181
• Identity: 309/1181 - (26%)
• Similarity: 484/1181 - (40%)
• Gaps: 306/1181 - (25%)

  Fly     7 VWLVFFCALGCLIHDADLRSIQPKASQCGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYG 71
            |.||...|.||:               |    .|..:|  :...::.|:|.||||:.||.:..:
 Frog     3 VLLVLLSAWGCV---------------C----THSAQP--IQAFVIPHSHMDVGWVYTVQESMH- 45

  Fly    72 SETKIQKAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQ-EAVKMLVEQGRLEFI 135
                   |....:..:|||.|:|...:|||.||..||..|||.....|: :.|..|:.:|||||:
 Frog    46 -------AYAANVYTTVVEELMRGDRRRFIVVEQEFFRLWWKLFAGNVEKQQVHQLMREGRLEFV 103

  Fly   136 GGAWSMNDEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGM 200
            .|...|:|||.|.....|.|.:.|...:.:|||.  |||..|.:||||.|....::||..||:|.
 Frog   104 IGGQVMHDEALTTIDDQILQLTEGHGFIYETFGV--RPRFSWHVDPFGASAASPTLFAMAGFNGH 166

  Fly   201 FFGRLDYQDKDERLMTKNAEMIWHGSANLGEEADLFSGAL---------YNNYQAPDGFCFD-IL 255
            ...|:||..|.:....|..:.||..|.:|.::.::|:..:         |..:....||.:: |.
 Frog   167 LISRIDYDTKADMQNGKELQFIWRASPSLSDKQEIFTHVMDQYSYCTPSYIPFSDRSGFYWNGIA 231

  Fly   256 CNDAPIIDGKHSPDNNVKERIDTFLDFAKT-------QSQYYRTNNIIVTMGGDFTYQAAQVYYK 313
            ....|..||.: |:.::....||...:|:|       ::.::|:::::...|.|..:..|.|.:.
 Frog   232 VFPDPPKDGMY-PNMSLPVTADTIHPYAETMVKNIKERAAWFRSSDVLWPWGCDKQFFNASVQFN 295

  Fly   314 NLDKLIRYGNERQANGSNINLLYSTPSCYLKSLHDAGITWPTK-SDDFFPYASDPHAYWTGYFTS 377
            |:|.|:.|.|:....|  :.:.|||...|.|:|::..:||..: |.||.||:||....|||::||
 Frog   296 NMDLLLDYINKHTEFG--VTVQYSTLGDYFKNLYNRNLTWGLRGSQDFLPYSSDSSQAWTGFYTS 358

  Fly   378 RPTLKRFERDGNHFLQVCKQLSALAP---KKP----------EEFDPHLTFMRETLGIMQHHDAI 429
            |..||...|..:..|...:  ||.|.   |.|          |:    |..:|..:..:||||.|
 Frog   359 RNVLKGVARRASSLLYAAE--SAFAQHLLKHPTGSVEKVWAMEQ----LRSLRWAVSEVQHHDGI 417

  Fly   430 TGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQSKDNVKDTSAKYVFEFKTCALLNITSCP 494
            ||||..||...|...:                   :|....|:...|..|.:..:.   ...||
 Frog   418 TGTESPKVRDMYIANL-------------------LQGAAGVRKLMAAIVMDLYSS---QANSC- 459

  Fly   495 VSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIIDNKGVTLESQAVPIPQVLIDIKHRNSTA- 558
               .|....:|:|||||..|..:|.:|:..|...:.|..|       .|:|..:     :|:|.
 Frog   460 ---GNGYINITVYNPLAWDVTTFVLVPMNNSVSGVYDKFG-------QPVPAQI-----QNATEP 509

  Fly   559 --KYEIVFLATNIPALGYRTYYVEKLDSTEGNT----------------RSKALPKRTSSVTVIG 605
              .:::..|.| :..|.|..|.: ||.|.:...                |:||  ||.:.||.|.
 Frog   510 SNAFDLHILVT-LKGLSYGRYSI-KLGSCDAANDRLVTGRKITFVRQPKRNKA--KRQNLVTPIM 570

  Fly   606 NSHIQLGFDTN-GFLSEVTA--DGLTRLVSQEFLFY-------EGAVGNNAEFLNRSSGAYIFRP 660
            |....:..|.| ..|..:||  ...|..|:||||.|       :|.:.:|  :|..|:|..|
 Frog   571 NDCYTVVIDQNTNLLHSITARESNQTVQVTQEFLEYHSNGDISKGPISDN--YLFTSTGPAI--- 630

  Fly   661 NENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVV-------RVYNKDS---------YAEFE 709
                  .|...|.:|:..|.||.|:.|.|...|:...       |:||...         :.|..
 Frog   631 ------SAYKAVGLEIIAGKLVTEIRQYFYSNITAQTYLYAVYSRIYNVPEGYDKSLVCHHIEQS 689

  Fly   710 WLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKINEAVAGNYYPI 774
            :.|||:.::    :|.|.|.::|:.:|.:..||:||.:|.:|:..:.||      ..||.||||:
 Frog   690 YRVGPMDLN----RESIIRTSTDLRTDRLIYTDNNGYQMQRRQFKNYDT------NTVARNYYPM 744

  Fly   775 TTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGE--ALNETEYGDGLIAR 837
            .....:||::.|:..|::||.|.||..:|.:|:|:||||..:..:.:..  .||:|.     :.|
 Frog   745 VRTAYIEDNSTRLVFLSERAHGVSSQDNGEVEIMLHRRLWNNLEWDLNYNLTLNDTS-----VVR 804

  Fly   838 GKHHLFFGKST------DREGVSLKGIERLTQLEKLLPTWKFFSNMEDYSADEWQTAFTNIFSGI 896
            ....|..|...      .|.|::|:        .:.|..:...:..|..|   ::|      :.:
 Frog   805 PTIWLMLGSRALAGALYQRLGMALE--------HRPLVIYSLHTGQEKRS---YKT------TDL 852

  Fly   897 SLVLPKPVHL--LTLEPW------HE-----------------NQLLVRFEHIMENGEDASYSQP 936
            .:.||..:||  |::..|      ||                 :::|:|.:|:.|..||...|:|
 Frog   853 PITLPDNIHLQILSIPGWFYSSRHHEHMQDIHTGNIRDNVADFHRVLLRLQHLYETNEDPVLSKP 917

  Fly   937 VQFNVKNVLSAF-DVEGIRETTLDGNAWLDESRRLQFAPDPEEAAFNTYATFSQPAESVHLLSAE 1000
            |..|::::|... .|..:.|.:|.| .|                             .:|.|...
 Frog   918 VTINLQSLLKGLGTVSLVEERSLTG-TW-----------------------------DIHTLKRW 952

  Fly  1001 KPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEGRSSKSTEGPYNSFKSDSSNQEYIIEL 1065
            |....:|..|:              |..|                          ....::.|.|
 Frog   953 KWKANIKGTDQ--------------REHT--------------------------LGTSDFTITL 977

  Fly  1066 SPMEIRTFIVY 1076
            ||.||||..||
 Frog   978 SPKEIRTLFVY 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	246/852 (29%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	89/293 (30%)
man2b2	NP_001106515.1	PLN02701	19..783	CDD:178304	245/847 (29%)
		GH38N_AMII_Epman_like	22..346	CDD:212122	104/336 (31%)