DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManI and AT3G26720

DIOPT Version :9

Sequence 1:	NP_001260350.1	Gene:	LManI / 34436	FlyBaseID:	FBgn0032253	Length:	950	Species:	Drosophila melanogaster
Sequence 2:	NP_189306.1	Gene:	AT3G26720 / 822284	AraportID:	AT3G26720	Length:	1019	Species:	Arabidopsis thaliana

Alignment Length:	996	Identity:	373/996 - (37%)
Similarity:	554/996 - (55%)	Gaps:	84/996 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 INVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKW 66
            |||||||||||||||||||||||.||.|.|:.|.||.:||:|:..||.|.:|:||.||..||.:|
plant    38 INVHLVPHSHDDVGWLKTVDQYYVGSNNSIRGACVQNVLDSVIASLLDDENRKFIYVEMAFFQRW 102

  Fly    67 YSEQTETVQRAVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGRPTVG 131
            :.:|:...:..|||||..|:|||..|...|:||||.||..::||..||.:::|..||..  |.||
plant   103 WRQQSNAKKVKVKKLVDSGQLEFINGGMCMHDEATPHYIDMIDQTTLGHQFIKTEFGQV--PRVG 165

  Fly   132 WQIDPFGHSREMASIF-AQMAFNGEFFARMDYVDKKQRMLDLEMEMIWQSSESL-KNSNIFTGML 194
            |||||||||...|.:. |:..|:..||||:||.|:.:|:.:..:|:|||.|:|| .:|.||||:.
plant   166 WQIDPFGHSAVQAYLLGAEFGFDSLFFARIDYQDRAKRLREKTLEVIWQGSKSLGSSSQIFTGVF 230

  Fly   195 YNHYSAPPGFCFDINCEDAPIIDGE-SYDNNVDARVSEFIDYVKNMSKSYRSTHIMVPMGDDFQY 258
            ..||..|.||.|:||...|||.|.. .:|.||..||::|:..........|:.|||..||.||:|
plant   231 PRHYDPPEGFTFEINDVSAPIQDDPLLFDYNVQERVNDFVAAALAQVNVTRTNHIMWLMGTDFRY 295

  Fly   259 EDAAVNFKNMDKLIKYVNDRQSTGSQVNVFYSTPSCYLYELHQLKQTWPNKTEDFFPYSSDSHSY 323
            :.|...|:.:||.|.|||    ...::||.|||||.|....:...::||.||:|||||:...::|
plant   296 QYAYSWFRQIDKFIHYVN----KDGRLNVLYSTPSIYTDAKYAANESWPLKTDDFFPYADKPNAY 356

  Fly   324 WTGYFTSRPTQKRFHRDGNHFFQTVKQLSVLANLSGTQYSEDLDNLSQAMGIMQHHDAVTGTEKQ 388
            |||||||||..|::.||.:.::...:||..|.....:..:.|:  |:.|:.|.||||||:||::|
plant   357 WTGYFTSRPAFKKYVRDLSGYYLAARQLEFLRGRDSSGPTTDM--LADALAIAQHHDAVSGTQRQ 419

  Fly   389 AVASDYDRLLFKAIVGAENSARDALRSLTNLTSG--------EFESCLELNISVCAFTQD---TA 442
            .||:||...|....:.||.....:|..|:...|.        :|:.|..||||.|..::.   :.
plant   420 HVAADYALRLSMGYLQAEKLVASSLSFLSAAKSSTEKKNPGTKFQQCPLLNISYCPASEARLLSG 484

  Fly   443 NNVIVTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREVFSEVVPVPWQVLALEHR---------P 498
            .:::|.:.|.|.....:.||||..:||.||.|..|:||..:::|:....|.:.:.         |
plant   485 KSLVVVVYNSLGWKREEVVRVPVSSENVIVKDASGKEVVFQLLPLSEIALRIRNEYVKAYLGRSP 549

  Fly   499 NDT-QHELVFEASVDKI--ANFLI-------RVLPSPKNIAEDQVQFPVERSQDELTVETSL--V 551
            .|| :|.|.|.|||..:  ::::|       |.| |...:....:...||..|..|.:..|.  |
plant   550 RDTAKHVLAFTASVPPLGFSSYVISDTGRTARGL-SASYVTSGSMNQNVEVGQGNLKLRYSEEGV 613

  Fly   552 KLTFDTTTGGLKTVKMNGFTENIQQTFGIYKGYRGNNGESKN-RSSGAYVFRPYGDIEIVN-NKV 614
            |:|...:|....|.:.:            |..|.|:||..|: ::||||||||.|.:.|.: .:.
plant   614 KITRHLSTKNQVTAEQS------------YAYYIGSNGTDKDPQASGAYVFRPDGVLPIKSKEEA 666

  Fly   615 ELSFYNGTKVKEVHQHVNEWISQVIRIYEDVNRVEFEWLVGPIPTDDDVGKEIITRFSSNISSKG 679
            :|:...|....||||.:|.||||:.|:|:..|..|.|:.:||||.||.:.|||||:.::.:.:.|
plant   667 QLTIVQGPLFDEVHQELNSWISQITRVYKGKNHAEIEFTIGPIPADDGISKEIITKLTTTMKTNG 731

  Fly   680 KFYTDSNGREILERERNQREHFTPDMSEAISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKD 744
            .||||||||:.::|.|:.|..:...:.:.::|||||:...|.:||....:::|.|||.||:||::
plant   732 TFYTDSNGRDFIKRIRDFRTDWDLQVYQPVAGNYYPLNLGIYMQDKTSELSVLVDRAVGGSSLEN 796

  Fly   745 GELELMLHRRLLNDDAFGVGEALNET----QYGTGLIARGKIYLILDAV-DGKPNQRLLQHQLDQ 804
            |::|||||||:.:||..||||.||||    :...||..:||.|:.:|.. ||...:|....::..
plant   797 GQIELMLHRRMQHDDIRGVGEILNETVCLPEGCKGLTIQGKFYVQIDKPGDGAKWRRTFGQEIYS 861

  Fly   805 HFWKFFSKSNGVASVNR-----NMIPDFFGIPESVELLSLEPYSKDQILIRLENFNTEGNVVSFN 864
            .....|::..|.:.:|.     :.....:.:|::|.||:|:.....::|:||.:....|....::
plant   862 PLLIAFTEQEGDSWINSHKTTFSAFEPSYSLPKNVALLTLQELENGEVLLRLAHLFEVGEDSEYS 926

  Fly   865 IY------PLFESLDGYQIWETTLDGNMLLEDVKRFKFAQDGTGSIPSSVEYYHAPHNPLTANST 923
            :.      .||.:....::.||:|.||....::::.:......||....|:          ....
plant   927 VMAKVELKKLFHNKKIREVKETSLSGNQEKAEMEKRRLIWKVEGSAGEEVK----------RGEA 981

  Fly   924 MNASGFVVTLVPMQIRTFIIQ 944
            ::|...||.||||:|||.:|:
plant   982 VDAEKLVVELVPMEIRTLLIK 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManI	NP_001260350.1	GH38N_AMII_LAM_like	2..276	CDD:212121	137/276 (50%)
		Alpha-mann_mid	323..398	CDD:286360	33/74 (45%)
		Glyco_hydro_38C	536..941	CDD:285047	139/424 (33%)
AT3G26720	NP_189306.1	PLN02701	36..997	CDD:178304	369/989 (37%)
AT3G26720	NP_189306.1	GH38N_AMII_LAM_like	38..314	CDD:212121	139/281 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840