Protein Alignment LManI and man2b2

DIOPT Version :10

• Sequence 1: NP_609407.1
• Gene: LManI / 34436
• FlyBaseID: FBgn0032253
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_001106515.1
• Gene: man2b2 / 100127706
• XenbaseID: XB-GENE-1006292
• Length: 990
• Species: Xenopus tropicalis
• Alignment Length: 1058
• Identity: 284/1058 - (26%)
• Similarity: 449/1058 - (42%)
• Gaps: 208/1058 - (19%)

  Fly     2 INVHLVPHSHDDVGWLKTVDQYYYGSQNKIQHAGVQYILDTVVEELLKDSSRRFIQVETFFFAKW 66
            |...::||||.||||:.||.:        ..||....:..||||||::...||||.||..||..|
 Frog    22 IQAFVIPHSHMDVGWVYTVQE--------SMHAYAANVYTTVVEELMRGDRRRFIVVEQEFFRLW 78

  Fly    67 YSEQTETVQR-AVKKLVAQGRLEFAGGAWSMNDEATVHYQSVVDQFNLGLRYLKDTFGDCGRPTV 130
            :......|:: .|.:|:.:|||||..|...|:|||.......:.|...|..::.:|||  .||..
 Frog    79 WKLFAGNVEKQQVHQLMREGRLEFVIGGQVMHDEALTTIDDQILQLTEGHGFIYETFG--VRPRF 141

  Fly   131 GWQIDPFGHSREMASIFAQMAFNGEFFARMDYVDKKQRMLDLEMEMIWQSSESLKN-SNIFTGML 194
            .|.:||||.|....::||...|||...:|:||..|.......|::.||::|.||.: ..|||.::
 Frog   142 SWHVDPFGASAASPTLFAMAGFNGHLISRIDYDTKADMQNGKELQFIWRASPSLSDKQEIFTHVM 206

  Fly   195 ---------YNHYSAPPGFCFD-INCEDAPIIDGESYDNNVDARVSEFIDYVKNMSKS------- 242
                     |..:|...||.:: |.....|..||...:.::.........|.:.|.|:
 Frog   207 DQYSYCTPSYIPFSDRSGFYWNGIAVFPDPPKDGMYPNMSLPVTADTIHPYAETMVKNIKERAAW 271

  Fly   243 YRSTHIMVPMGDDFQYEDAAVNFKNMDKLIKYVNDRQSTGSQVNVFYSTPSCYLYELHQLKQTWP 307
            :||:.::.|.|.|.|:.:|:|.|.|||.|:.|:|.....|  |.|.|||...|...|:....||.
 Frog   272 FRSSDVLWPWGCDKQFFNASVQFNNMDLLLDYINKHTEFG--VTVQYSTLGDYFKNLYNRNLTWG 334

  Fly   308 NK-TEDFFPYSSDSHSYWTGYFTSRPTQKRFHRDGNHFFQTVKQL---SVLANLSGTQYS----E 364
            .: ::||.||||||...|||::|||...|...|..:......:..   .:|.:.:|:...    |
 Frog   335 LRGSQDFLPYSSDSSQAWTGFYTSRNVLKGVARRASSLLYAAESAFAQHLLKHPTGSVEKVWAME 399

  Fly   365 DLDNLSQAMGIMQHHDAVTGTEKQAVASDYDRLLFKAIVGAENSARDALRSLT-NLTSGEFESCL 428
            .|.:|..|:..:||||.:||||...|...|...|.:...|    .|..:.::. :|.|.:..||
 Frog   400 QLRSLRWAVSEVQHHDGITGTESPKVRDMYIANLLQGAAG----VRKLMAAIVMDLYSSQANSC- 459

  Fly   429 ELNISVCAFTQDTANNVI-VTLVNPLAHSSTQYVRVPAKNENYIVTDEKGREVFSEVVPVPWQVL 492
                         .|..| :|:.||||...|.:|.||..|....|.|:.|:       |||.|:
 Frog   460 -------------GNGYINITVYNPLAWDVTTFVLVPMNNSVSGVYDKFGQ-------PVPAQI- 503

  Fly   493 ALEHRPNDTQHELVFEASVDKIANFLIRVLPSPKNIAEDQVQFPV---ERSQDELTVETSLVKLT 554
                 .|.|:....|:          :.:|.:.|.::..:....:   :.:.|.|....   |:|
 Frog   504 -----QNATEPSNAFD----------LHILVTLKGLSYGRYSIKLGSCDAANDRLVTGR---KIT 550

  Fly   555 F---------------------------DTTTGGLKTVKMNGFTENIQQTFGIYKGYRGNNGESK 592
            |                           |..|..|.::......:.:|.|....: |..|...||
 Frog   551 FVRQPKRNKAKRQNLVTPIMNDCYTVVIDQNTNLLHSITARESNQTVQVTQEFLE-YHSNGDISK 614

  Fly   593 NRSSGAYVFRPYGDIEIVNNKVELSFYNGTKVKEVHQHVNEWISQVIRIYEDVNR---------- 647
            ...|..|:|...|........|.|....|..|.|:.|:....|:....:|...:|
 Frog   615 GPISDNYLFTSTGPAISAYKAVGLEIIAGKLVTEIRQYFYSNITAQTYLYAVYSRIYNVPEGYDK 679

  Fly   648 ------VEFEWLVGPIPTDDDVGKEIITRFSSNISSKGKFYTDSNGREILERERNQREHFTPDMS 706
                  :|..:.|||:    |:.:|.|.|.|:::.:....|||:||.::      ||..|....:
 Frog   680 SLVCHHIEQSYRVGPM----DLNRESIIRTSTDLRTDRLIYTDNNGYQM------QRRQFKNYDT 734

  Fly   707 EAISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDAFGVGE--ALNE 769
            ..::.||||:.....::|:..|:..|::||.|.:|..:||:|:||||||.|:..:.:..  .||:
 Frog   735 NTVARNYYPMVRTAYIEDNSTRLVFLSERAHGVSSQDNGEVEIMLHRRLWNNLEWDLNYNLTLND 799

  Fly   770 TQYGTGLIARGKIYLILD--AVDGKPNQRL---LQHQLDQHFWKFFSKSNG--VASVNRNMIPDF 827
            |.     :.|..|:|:|.  |:.|...|||   |:|:.    ...:|...|  ..|.....:|
 Frog   800 TS-----VVRPTIWLMLGSRALAGALYQRLGMALEHRP----LVIYSLHTGQEKRSYKTTDLP-- 853

  Fly   828 FGIPESV--ELLSLEP--YSK---------------------DQILIRLEN-FNTE-----GNVV 861
            ..:|:::  ::||:..  ||.                     .::|:||:: :.|.     ...|
 Frog   854 ITLPDNIHLQILSIPGWFYSSRHHEHMQDIHTGNIRDNVADFHRVLLRLQHLYETNEDPVLSKPV 918

  Fly   862 SFNIYPLFESLDGYQ-IWETTLDGNMLLEDVKRFKFAQDGTGSIPSSVEYYHAPHNPLTANSTMN 925
            :.|:..|.:.|.... :.|.:|.|...:..:||:|:    ..:|..:.:..|          |:.
 Frog   919 TINLQSLLKGLGTVSLVEERSLTGTWDIHTLKRWKW----KANIKGTDQREH----------TLG 969

  Fly   926 ASGFVVTLVPMQIRTFII 943
            .|.|.:||.|.:|||..:
 Frog   970 TSDFTITLSPKEIRTLFV 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManI	NP_609407.1	GH38N_AMII_LAM_like	2..276	CDD:212121	97/292 (33%)
		PLN02701	4..765	CDD:178304	235/835 (28%)
man2b2	NP_001106515.1	PLN02701	19..783	CDD:178304	233/827 (28%)
		GH38N_AMII_Epman_like	22..346	CDD:212122	112/335 (33%)