Protein Alignment TfIIB and BRF1

DIOPT Version :10

• Sequence 1: NP_476888.1
• Gene: TfIIB / 34430
• FlyBaseID: FBgn0004915
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_011762.1
• Gene: BRF1 / 853161
• SGDID: S000003478
• Length: 596
• Species: Saccharomyces cerevisiae
• Alignment Length: 282
• Identity: 70/282 - (24%)
• Similarity: 130/282 - (46%)
• Gaps: 34/282 - (12%)

  Fly    30 DMICSECGLVVGDR--VIDVGSEWRTFSNEKSGVDPSRVGGPENPLLSGGDLSTIIGPGTGSASF 92
            |::|..||:|..|.  |.:|     ||....:|.          .::.|    :.||.|...|:|
Yeast    22 DLVCKACGVVSEDNPIVSEV-----TFGETSAGA----------AVVQG----SFIGAGQSHAAF 67

  Fly    93 DAFGAPKYQNRRTMSSSDRSLISAFKEISSMADRINLPKTIVDRANNLFKQVHDGKNLKGRSNDA 157
            ....|        :.|.:.:|.:|.:::.:::..:::|:.|.|.|...:|.......::||.:..
Yeast    68 GGSSA--------LESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQN 124

  Fly   158 KASACLYIACRQEGVPRTFKEICAVSKISKKEIGRCFKLTLKALE-TSVDLITTADFMCRFCANL 221
            ..::|||:|||:|.......:..:..::|...||..|...:|.|. |.:.|...:.|:..|...|
Yeast   125 VIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKL 189

  Fly   222 DLPN---MVQRAATHIAKKAVEMDIVPGRSPISVAAAAIYMASQASEHKRSQKEIGDIAGVADVT 283
            ||.:   .|.:.|..:|::..:..:..||.|..:|.|.|.:|.:.:..:|:..||..::.||:.|
Yeast   190 DLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEET 254

  Fly   284 IRQSY-KLMYPHAAKLFPEDFK 304
            ::|.. :.....||||..:.|:
Yeast   255 LQQRLNEFKNTKAAKLSVQKFR 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIB	NP_476888.1	SUA7	1..289	CDD:441015	65/265 (25%)
BRF1	NP_011762.1	TF_Zn_Ribbon	3..45	CDD:400527	10/27 (37%)
		CYCLIN_TFIIIB90_rpt1	78..168	CDD:410256	21/89 (24%)
		CYCLIN_TFIIIB90_rpt2	174..265	CDD:410257	23/90 (26%)
		BRF1	463..595	CDD:462250