DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdfy2 and TAF5

DIOPT Version :9

Sequence 1:	NP_001188779.1	Gene:	Wdfy2 / 34425	FlyBaseID:	FBgn0032246	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_197897.3	Gene:	TAF5 / 832586	AraportID:	AT5G25150	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	329	Identity:	72/329 - (21%)
Similarity:	123/329 - (37%)	Gaps:	80/329 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKPAQRTNNDRFNTSKKPELLSKLEGSSDDVNAAIL----------------------IPGENGV 47
            :.||.|.         ||||  .|...|.||..:||                      :...||:
plant   302 VSPAPRV---------KPEL--ALPVMSTDVEQSILEDLRNRVQLSSVAMPSVSFYTFVNTHNGL 355

  Fly    48 --ISVS----------DDKTVRVWLKRDSGQYWPSICQYMPSGCTAIEYVSESRHLYVGQENGTV 100
              .|:|          .|.:::||.....||          :|..|::..::|....:| .||.
plant   356 NCSSISHDGSLVAGGFSDSSIKVWDMAKIGQ----------AGSGALQAENDSSDQSIG-PNGR- 408

  Fly   101 TQYALSEDCNRLSFLRDYLSHQARVMAVVFSKTHKWILSAGKDKQFAYHCTESGKRV---GGYNF 162
            ..|.|            .|.|...|.:..||....::||:..|.......|:....:   .|:|:
plant   409 RSYTL------------LLGHSGPVYSATFSPPGDFVLSSSADTTIRLWSTKLNANLVCYKGHNY 461

  Fly   163 ETPCTALQFDALAKYAFVGDHAGQITMLRCDVQGVQLITTFNGHSAEIRCLKWVEGPQLLFSGAC 227
              |....||.....|.....|.....:...|  .:|.:....||.:::.|::|......:.:|:.
plant   462 --PVWDAQFSPFGHYFASCSHDRTARIWSMD--RIQPLRIMAGHLSDVDCVQWHPNCNYIATGSS 522

  Fly   228 DQSVLVWDV-GGKRGTIYELQGHSNKVSALSYANHTQQLISCGEDSVVVFWEMNAMRKEVPGWVD 291
            |::|.:||| .|:...|:  .||.:.|.:|:.:...:.:.|..||..::.|:::..|...| .:.
plant   523 DKTVRLWDVQTGECVRIF--IGHRSMVLSLAMSPDGRYMASGDEDGTIMMWDLSTARCITP-LMG 584

  Fly   292 TNNC 295
            .|:|
plant   585 HNSC 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdfy2	NP_001188779.1	WD40	4..405	CDD:225201	72/329 (22%)
		WD40	24..279	CDD:295369	62/292 (21%)
		WD40 repeat	35..72	CDD:293791	12/70 (17%)
		WD40 repeat	80..117	CDD:293791	7/36 (19%)
		WD40 repeat	125..161	CDD:293791	8/38 (21%)
		WD40 repeat	166..205	CDD:293791	6/38 (16%)
		WD40 repeat	211..248	CDD:293791	10/37 (27%)
		WD40 repeat	253..283	CDD:293791	6/29 (21%)
		FYVE_WDFY1_like	287..356	CDD:277258	3/9 (33%)
		WD40 repeat	324..371	CDD:293791
TAF5	NP_197897.3	TFIID_NTD2	64..188	CDD:398277
		WD40 repeat	357..416	CDD:293791	15/82 (18%)
		WD40	414..663	CDD:238121	42/182 (23%)
		WD40 repeat	422..458	CDD:293791	6/35 (17%)
		WD40 repeat	463..499	CDD:293791	6/37 (16%)
		WD40 repeat	506..541	CDD:293791	10/36 (28%)
		WD40 repeat	547..583	CDD:293791	8/36 (22%)
		WD40 repeat	589..622	CDD:293791	72/329 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910