DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wdfy2 and Wdr46

DIOPT Version :9

Sequence 1:NP_001188779.1 Gene:Wdfy2 / 34425 FlyBaseID:FBgn0032246 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_997656.1 Gene:Wdr46 / 309628 RGDID:2209 Length:609 Species:Rattus norvegicus


Alignment Length:337 Identity:72/337 - (21%)
Similarity:111/337 - (32%) Gaps:98/337 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 RFNTSK-----KPELLSKL--------EGSSDDVNAAILIPGENGVISVSDDKTVRVWLKRD--- 63
            |.:.||     ||:..|:|        |.|.....|.:|:..|.|.:...|.:.....|:.|   
  Rat   113 RIDKSKKLPHSKPKTQSQLEKAEAQEEEASVRAARAELLLAEEPGFLVGEDGEDTAKILQTDIVE 177

  Fly    64 -------SGQYWPSICQYMPSGCTAIEYVSESRHLYVGQENG------TVTQYALSEDCNRLSFL 115
                   :..:..::.|:.|   ..:.|....|||.:|...|      .||:..:.| .|....:
  Rat   178 AVDISSAAKHFDLNLRQFGP---YRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCE-INVTEAV 238

  Fly   116 RD-YLSHQARVMAVVFSKTHKWILSAGKDKQ-FAYHCTESGKRVGGYNFETPCTALQFDALAKYA 178
            || :..|...::||.   .::|:..  .|.| ...||.....||         |.|:|.......
  Rat   239 RDIHFLHSEALLAVA---QNRWLYI--YDNQGIELHCIRRCDRV---------TRLEFLPFHFLL 289

  Fly   179 FVGDHAGQITMLRCDVQGVQLITTFN--------------------GHS---------------A 208
            ......|.:|.|  ||...:::|..|                    |||               |
  Rat   290 ATASETGFLTYL--DVSVGKIVTALNARAGRLNVMAQNPYNAVIHLGHSNGTVSLWSPAMKEPLA 352

  Fly   209 EIRCLKW--------VEGPQLLFSGACDQSVLVWDVGGKRGTIYELQGHSNKVSALSYANHTQQL 265
            :|.|.:.        ..|..:..|| .|..:.::|:   |||...|...:....|...|...:.|
  Rat   353 KILCHRGGVRAVGVDSTGTYMATSG-LDHQLKIFDL---RGTFQPLSSRTLPQGAGHLAFSQRGL 413

  Fly   266 ISCGEDSVVVFW 277
            :..|...||..|
  Rat   414 LVAGMGDVVNIW 425

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wdfy2NP_001188779.1 WD40 4..405 CDD:225201 72/337 (21%)
WD40 24..279 CDD:295369 67/323 (21%)
WD40 repeat 35..72 CDD:293791 7/46 (15%)
WD40 repeat 80..117 CDD:293791 10/42 (24%)
WD40 repeat 125..161 CDD:293791 9/36 (25%)
WD40 repeat 166..205 CDD:293791 10/58 (17%)
WD40 repeat 211..248 CDD:293791 10/44 (23%)
WD40 repeat 253..283 CDD:293791 7/25 (28%)
FYVE_WDFY1_like 287..356 CDD:277258
WD40 repeat 324..371 CDD:293791
Wdr46NP_997656.1 Rubella_Capsid 5..>75 CDD:283420
WD40 repeat 198..234 CDD:293791 9/36 (25%)
WD40 <202..389 CDD:225201 43/207 (21%)
WD40 <207..386 CDD:295369 41/196 (21%)
WD40 repeat 239..273 CDD:293791 10/38 (26%)
WD40 repeat 277..313 CDD:293791 10/46 (22%)
WD40 repeat 320..355 CDD:293791 4/34 (12%)
WD40 354..>447 CDD:295369 18/76 (24%)
WD40 repeat 361..398 CDD:293791 9/40 (23%)
WD40 repeat 406..442 CDD:293791 6/20 (30%)
BING4CT 439..517 CDD:198101
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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