DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdfy2 and Plekhf1

DIOPT Version :9

Sequence 1:	NP_001188779.1	Gene:	Wdfy2 / 34425	FlyBaseID:	FBgn0032246	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001013166.1	Gene:	Plekhf1 / 308543	RGDID:	1310544	Length:	279	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	38/161 - (23%)
Similarity:	61/161 - (37%)	Gaps:	43/161 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 VSALS------YANHTQ-----QLISCGEDSVVVFWEMNAMRKEVPGWVDTNNCQLCSRPFFWNF 306
            |||.|      :.:|.:     ||::.|.....         :....|:......:|.|.....|
  Rat   111 VSAASTTERQEWISHIEECVRRQLLATGRQPTT---------EHAAPWIPDKATDICMRCTQTRF 166

  Fly   307 RSMMDQKQLGIRQHHCRHCGKAVCDNCSTNRINIPIMGFEFDVRTCDPCYKQLQTVERPSLAS-- 369
            .::       .|:||||.||..||..||..|..:|.:..: .:|.|..||::|...:|...|.
  Rat   167 SAL-------TRRHHCRKCGFVVCAECSRERFLLPRLSPK-PLRVCSLCYRELAAQKRREEAKER 223

  Fly   370 FNDAKHSIVYM-------------DLDEDRK 387
            |..:...:.::             |.||||:
  Rat   224 FRGSPGQLTHLGSTMCGASSGDDDDSDEDRE 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdfy2	NP_001188779.1	WD40	4..405	CDD:225201	38/161 (24%)
		WD40	24..279	CDD:295369	8/36 (22%)
		WD40 repeat	35..72	CDD:293791
		WD40 repeat	80..117	CDD:293791
		WD40 repeat	125..161	CDD:293791
		WD40 repeat	166..205	CDD:293791
		WD40 repeat	211..248	CDD:293791
		WD40 repeat	253..283	CDD:293791	8/40 (20%)
		FYVE_WDFY1_like	287..356	CDD:277258	19/68 (28%)
		WD40 repeat	324..371	CDD:293791	15/48 (31%)
Plekhf1	NP_001013166.1	PH_Phafin2-like	7..129	CDD:269927	5/17 (29%)
		PH	39..131	CDD:278594	5/19 (26%)
		FYVE_PKHF1	148..211	CDD:277293	21/70 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..264		7/36 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910