Protein Alignment Cdk1 and CDK13

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: XP_016868239.1
• Gene: CDK13 / 8621
• HGNCID: 1733
• Length: 1542
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 119/328 - (36%)
• Similarity: 186/328 - (56%)
• Gaps: 50/328 - (15%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            ::.|:.|..|||||||.|||.|::.||::||:||:||:::.||.|.||||||.:|::|.|::|:.
Human   702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIIN 766

  Fly    66 LEDVL----------MEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCH 120
            :::::          .::...||:||::..||...::|..|  |.....::|::.|:...:.:||
Human   767 MKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLV--HFNENHIKSFMRQLMEGLDYCH 829

  Fly   121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGR-------------------------------SFG 154
            ::..||||:|..|:|::..|.||:|||||.|                               |||
Human   830 KKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESAWLMLIWEKVIFIWRILLMQMSAGSFG 894

  Fly   155 IPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRI 219
            ...|.||::::|||||.||:|||..||:..:|:||.|||..|:.|:||:||.:.|:.||..:.||
Human   895 DSSRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRI 959

  Fly   220 LKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKN----LDANGIDLIQKMLIYDPVHRISAKD 280
            ..:|...:||.|..|| |.||..  ...|...:|:.    :.|..:||...||..||..|.:|:.
Human   960 CGSPCPAVWPDVIKLP-YFNTMK--PKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQ 1021

  Fly   281 ILE 283
            .|:
Human  1022 ALQ 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	119/326 (37%)
CDK13	XP_016868239.1	STKc_CDK12	697..1028	CDD:270847	119/328 (36%)