DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and AgaP_AGAP002986

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_311901.5	Gene:	AgaP_AGAP002986 / 1272970	VectorBaseID:	AGAP002986	Length:	794	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	70/283 - (24%)
Similarity:	129/283 - (45%)	Gaps:	32/283 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLED 68
            :.|:||||:|..|.||......||..||:|::.|....:  ....|.||.:::|.||.|:|...|
Mosquito   520 YNKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPK--KELIINEILVMRENKHPNVVNYLD 582

  Fly    69 VLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQN 133
            ..:....::::.|:|.   ...:..:..:..|:...:.:...::..|:.|.|..:|:|||:|..|
Mosquito   583 SYLVSEELWVVMEYLP---GGSLTDVVTETCMDEGQIAAVCREVLQALEFLHSNQVIHRDIKSDN 644

  Fly   134 LLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMA 198
            :|:...|.:|:.|||............|..:.|.::.||||:. ..:|...||:||:|.:..||.
Mosquito   645 ILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVT-RKQYGPKVDLWSLGIMAIEMI 708

  Fly   199 TRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDL 263
            ..:|.:..::.:..|:    ::.|..:         |:.|             :.:.|.....|.
Mosquito   709 EGEPPYLNENPLRALY----LIATHGK---------PEIK-------------EKEKLSTVFQDF 747

  Fly   264 IQKMLIYDPVHRISAKDILEHPY 286
            :.:.|..|...|.:|.::|.||:
Mosquito   748 LDQCLEVDVDQRATAYELLRHPF 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	70/283 (25%)
AgaP_AGAP002986	XP_311901.5	CRIB_PAK_like	83..128	CDD:238526
		STKc_PAK_I	512..772	CDD:270814	70/283 (25%)
		S_TKc	520..771	CDD:214567	70/283 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910