DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and AgaP_AGAP009459

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	XP_307878.4	Gene:	AgaP_AGAP009459 / 1269259	VectorBaseID:	AGAP009459	Length:	298	Species:	Anopheles gambiae

Alignment Length:	291	Identity:	242/291 - (83%)
Similarity:	274/291 - (94%)	Gaps:	0/291 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            ||||:||||||||||||||||||:.||:||||||||||::|||:||||||||||||||||.|:|.
Mosquito     1 MEDFQKIEKIGEGTYGVVYKGRNKHTGEIVAMKKIRLETEDEGIPSTAIREISLLKELKHRNVVS 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |:||||||||:|||||||||||||||||||.:|.::::||:||:||||:|:||||||||||||||
Mosquito    66 LKDVLMEENRLYLIFEFLSMDLKKYMDSLPPEKMIDADLVKSYMYQITAAMLFCHRRRVLHRDLK 130

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||:|.|:|||||||||||||||||.|||||||||||||||||||.||||||||||||||||
Mosquito   131 PQNLLINKEGVIKVADFGLGRSFGIPVRNYTHEIVTLWYRAPEVLLGSLRYSCPVDIWSIGCIFA 195

  Fly   196 EMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANG 260
            |||||||||||||||||||||||||:|||:|||||||||||||::||||:.|.|.:|:.|||:.|
Mosquito   196 EMATRKPLFQGDSEIDQLFRMFRILRTPTDDIWPGVTSLPDYKSSFPCWTQNNLASQVSNLDSAG 260

  Fly   261 IDLIQKMLIYDPVHRISAKDILEHPYFNGFQ 291
            |||:||.|||||:.|||||.||||.||:||:
Mosquito   261 IDLLQKCLIYDPMLRISAKKILEHKYFDGFE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	236/283 (83%)
AgaP_AGAP009459	XP_307878.4	PLN00009	1..291	CDD:177649	241/289 (83%)
AgaP_AGAP009459	XP_307878.4	STKc_CDK1_euk	3..287	CDD:270845	236/283 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	496	1.000	Domainoid score	I1250
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68203
Inparanoid	1	1.050	508	1.000	Inparanoid score	I2990
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	1	1.000	-	-		oto106617
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X960
TreeFam	1	0.960	-	-
	12	11.930