Protein Alignment lft and lix1

DIOPT Version :10

• Sequence 1: NP_609390.1
• Gene: lft / 34405
• FlyBaseID: FBgn0032230
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_001313325.1
• Gene: lix1 / 558010
• ZFINID: ZDB-GENE-060526-123
• Length: 290
• Species: Danio rerio
• Alignment Length: 251
• Identity: 133/251 - (52%)
• Similarity: 179/251 - (71%)
• Gaps: 9/251 - (3%)

  Fly    19 EDRDYR-VNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCP 82
            :||.:: :|||..|.:||:.||:.|..::...||:||||||.|.|:||:||||||||||:|::|.
Zfish     8 DDRAFKDLNVVGMLHKFWEQKQAAGVMMEIENLVVYESIPSPSPPFICYVTLPGGSCFGNFKHCY 72

  Fly    83 TKAEARRSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLE 147
            :||||||.:|::|||||.|||.|.|||:.|||..:|::|.::..|.........:.|||:..|||
Zfish    73 SKAEARRDAARVALMNSTFNELPCRRITPEFISHSVKEAVSTTSGNIADASDPSTSIGAYCLMLE 137

  Fly   148 ANKGRTMLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREH 212
            .|.|:|||||||:|||||||||||:|||.|:..||||||:.:||.:.||:..||.|||||:.:|.
Zfish   138 LNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKEL 202

  Fly   213 DNPGVIRRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLGGSALNSATIDD 268
            .:||::.:||.||.:||...|..||||||.||||:||.:        ||:.|..:|
Zfish   203 QSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSL--------ALSHADAED 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lft	NP_609390.1	LIX1	24..255	CDD:464400	127/231 (55%)
lix1	NP_001313325.1	LIX1	6..245	CDD:464400	131/244 (54%)