DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ClpP and Clpp

DIOPT Version :9

Sequence 1:	NP_001260332.1	Gene:	ClpP / 34402	FlyBaseID:	FBgn0032229	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_059089.1	Gene:	Clpp / 53895	MGIID:	1858213	Length:	272	Species:	Mus musculus

Alignment Length:	244	Identity:	150/244 - (61%)
Similarity:	182/244 - (74%)	Gaps:	18/244 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TAVSRFLQISSVQCGGRANSVRNINLIPMVVEQTGRGERAYDIFSRLLKERIICLMGNITDDISS 68
            ||||    .|.::......:.|...|||:||||||||||||||:||||:|||:|:||.|.|.::|
Mouse    33 TAVS----CSPLRRSLHGTATRAFPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVAS 93

  Fly    69 TVVAQLLFLQSENVNKPIHLYINSPGGVVTAGLAIYDTMQYVKPPIATWCVGQACSMGSLLLAAG 133
            .|:|||||||||:..||||:|||||||||||||||||||||:..||.|||||||.||||||||||
Mouse    94 LVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAG 158

  Fly   134 APGMRYSLPNARIMIHQPSGGAQGQATDILIHAEEIIKIKRQLTNIYVKHAKNTYEEMSGRMERD 198
            :||||:||||:|||||||||||:||||||.|.||||:|:|:||.|||.||.|.:.:.:...||||
Mouse   159 SPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERD 223

  Fly   199 HFMTPEEAKVLGIIDHVLEHPPETVSETGPASDGGVTSGKAVPEECEKK 247
            .:|:|.||:..||:|.||.|||:              .|:..||..:|:
Mouse   224 RYMSPMEAQEFGILDKVLVHPPQ--------------DGEDEPELVQKE 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ClpP	NP_001260332.1	clpP	28..222	CDD:178955	140/193 (73%)
Clpp	NP_059089.1	clpP	53..245	CDD:178955	138/191 (72%)
Clpp	NP_059089.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..272		9/33 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845773
Domainoid	1	1.000	267	1.000	Domainoid score	I1866
eggNOG	1	0.900	-	-		E1_COG0740
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4385
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2750
Isobase	1	0.950	-	0	Normalized mean entropy	S2542
OMA	1	1.010	-	-		QHG58140
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004853
OrthoInspector	1	1.000	-	-		oto91995
orthoMCL	1	0.900	-	-		OOG6_100939
Panther	1	1.100	-	-	LDO	PTHR10381
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2456
SonicParanoid	1	1.000	-	-		X3980
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740