DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5367 and ctsz

DIOPT Version :9

Sequence 1:	NP_609387.1	Gene:	CG5367 / 34401	FlyBaseID:	FBgn0032228	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001106427.1	Gene:	ctsz / 100127597	XenbaseID:	XB-GENE-959211	Length:	296	Species:	Xenopus tropicalis

Alignment Length:	227	Identity:	69/227 - (30%)
Similarity:	105/227 - (46%)	Gaps:	39/227 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 MANVPESLDWRS---KGFITPPYNQ---LSCGSCYAFSIAESIMGQV-FKRTGKILS--LSKQQI 179
            ::.:|:..|||:   ..:::...||   ..||||:|.....::..:: .||.|...|  ||.|.:
Frog    50 VSELPKVWDWRNLNGTNYVSTTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGVWPSAYLSVQHV 114

  Fly   180 VDCSVSHGNQG-CVGGSLRNTLSYLQSTGGIMRDQDYPYVARKGKCQ----------FVPDLSVV 233
            :||:    |.| |.||.......|..| .||..:....|.||..||.          |.....:.
Frog   115 IDCA----NAGSCEGGDHGGVWEYANS-HGIPDETCNNYQARDQKCDKFNQCGTCVTFGKCFYLS 174

  Fly   234 NVTSWAI---LPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDD--PLCSSASVNHAMV 293
            |.|.|.:   ..|...:.:.|.:...||::..|.|:.| ...|:.|:|.:  |   ||.:||.:.
Frog   175 NYTLWKVGDFGSVSGREKMMAEIYKNGPISCGIMATEK-LDAYTGGLYAEYQP---SAMINHIVS 235

  Fly   294 VIGFGKD-----YWILKNWWGQNWGENGYIRI 320
            |.|:|.|     |||::|.||:.|||.|::||
Frog   236 VAGWGLDESGAEYWIVRNSWGEPWGERGWLRI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458
CG5367	NP_609387.1	Peptidase_C1A	128..336	CDD:239068	69/223 (31%)
ctsz	NP_001106427.1	Peptidase_C1A_CathepsinX	53..294	CDD:239149	69/224 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010