Protein Alignment Cdk5alpha and cdk5r1

DIOPT Version :9

• Sequence 1: NP_001260320.1
• Gene: Cdk5alpha / 34385
• FlyBaseID: FBgn0027491
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: XP_002935561.1
• Gene: cdk5r1 / 100497533
• XenbaseID: XB-GENE-1032903
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 134/339 - (39%)
• Similarity: 179/339 - (52%)
• Gaps: 95/339 - (28%)

  Fly   125 EKSSFEKNLKKHSIFINALSWKKLSTSHNKKKIENKNKCANLPTACFKAQLLESSFASSSDKNRN 189
            :.|...|:||:||| |:.|.||:|....:||:...|.:                  |:.|.:|
 Frog    31 QNSKNGKSLKRHSI-ISVLPWKRLVAVSSKKRQPKKGQ------------------ANGSYQN-- 74

  Fly   190 IQLHCNRIDEHNQQHCNQHPHPHPHQHQLQLQNQHQHQNQNQNQNQNQVQDIREEVMTGPPGKSQ 254
                       |..|.|                                              |:
 Frog    75 -----------NITHLN----------------------------------------------SE 82

  Fly   255 NPSKAKDPVKVNNKNSMSNHNK-LIQK---QPLTLSLPQQVQASSIQTKNTNQIPRKTVIQASTS 315
            |..|:   :...|.:|.:...| .:.|   ..:|.:..||:.||          |::.|:|||||
 Frog    83 NLKKS---ISCANLSSFTQDTKDSLSKGVGASITKAAGQQIHAS----------PKRVVVQASTS 134

  Fly   316 ELLKCLGMFLHCRCQRLNNFDAGDAVMWLRAVDRSLLLQGWQDVAFINPANVVFVYMLVRELVSG 380
            |||:|||.||..||.:|.:....:.|:|||:||||||||||||..||.|||:||:|||.|:.:|.
 Frog   135 ELLRCLGEFLCRRCYKLKHLSPTEPVLWLRSVDRSLLLQGWQDQGFITPANIVFLYMLCRDTISS 199

  Fly   381 EESKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEKFWDRCLVIVNKLSDKMLKINAEP 445
            |.:.|.||||::|||:|||||||||||||||||||||:|||.||||||.|:..:|.|||:|||:|
 Frog   200 ELNTEQDLQAALLTCVYLSYSYMGNEISYPLKPFLVENSKEDFWDRCLSIITMMSAKMLRINADP 264

  Fly   446 GFFTEVFTELKSCG 459
            .:||::|.:|||.|
 Frog   265 QYFTQIFADLKSEG 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5alpha	NP_001260320.1	CDK5_activator	107..458	CDD:281279	132/336 (39%)
cdk5r1	XP_002935561.1	CDK5_activator	29..279	CDD:367424	134/339 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2554
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3029
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492547at2759
OrthoFinder	1	1.000	-	-		FOG0001633
OrthoInspector	1	1.000	-	-		otm47923
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3652
SonicParanoid	1	1.000	-	-		X1362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090