Protein Alignment CG5731 and NAGA

DIOPT Version :10

• Sequence 1: NP_609354.1
• Gene: CG5731 / 34355
• FlyBaseID: FBgn0032192
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_000253.1
• Gene: NAGA / 4668
• HGNCID: 7631
• Length: 411
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 211/401 - (52%)
• Similarity: 268/401 - (66%)
• Gaps: 22/401 - (5%)

  Fly    18 LDNGLAKTPPMGWLSWERFRCNTDCVNDPDNCISEQLFQTMTDIVVADGYASVGYEYINIDDCWL 82
            |||||.:|||||||:|||||||.:|..||.||||||||..|.|.:..||:..:||.|:||||||:
Human    18 LDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWI 82

  Fly    83 EKHRSHDGKLVADRKRFPNGIKALSDYIHSRGLKFGIYEDYGNYTCAGYPG-IIGYEEKDALQFA 146
             ..|...|:|:.|.||||:||..|:||:||.|||.|||.|.||:||.|||| .:....:||..||
Human    83 -GGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFA 146

  Fly   147 DWNVDYVKLDGCYALPYDMDHGYSTFGRLLNSTGKSMVYSCSWPVYQIYAGIQP--NYSAIQTHC 209
            :|.||.:|||||::.|.:...||......||:||:.:.:|||||.|:  .|:.|  |||.:...|
Human   147 EWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYE--GGLPPRVNYSLLADIC 209

  Fly   210 NLWRNYDDIQDSWASVENIIDYYGNNQDVIAPNAGPGHWNDPDMLIIGNFGLSYEQAKTQFAIWS 274
            |||||||||||||.||.:|::::..:||::.|.||||||||||||:|||||||.||::.|.|:|:
Human   210 NLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWT 274

  Fly   275 ILAAPLLMSVDLRTIRPQFKHILQNRKIIAVDQDPLGIQGRRIYKHKG-IEIWSRPIGPLYQNFY 338
            :||||||||.|||||..|...||||..:|.::|||||||||||:|.|. ||::.||:    .|..
Human   275 VLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPL----SNKA 335

  Fly   339 SYAIAFVNRRTDGTPSDISVTLKELGLINFSG---YRVEDLYENVDYGVLYPNTKIKVKVNPSGV 400
            | |:.|.:.||| .|....   ..||.:||:|   |..:|:|.......|...|...|.:|||||
Human   336 S-ALVFFSCRTD-MPYRYH---SSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGV 395

  Fly   401 VMLKGEVQYPV 411
            ||.   ..||:
Human   396 VMW---YLYPI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5731	NP_609354.1	AmyAc_family	25..308	CDD:476817	161/285 (56%)
		Melibiase_2_C	311..399	CDD:407508	34/91 (37%)
NAGA	NP_000253.1	AmyAc_family	25..308	CDD:476817	161/285 (56%)
		Melibiase_2_C	311..394	CDD:407508	34/91 (37%)