Protein Alignment Trp1 and Sec62

DIOPT Version :10

• Sequence 1: NP_723510.1
• Gene: Trp1 / 34333
• FlyBaseID: FBgn0011584
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_001344457.1
• Gene: Sec62 / 69276
• MGIID: 1916526
• Length: 410
• Species: Mus musculus
• Alignment Length: 394
• Identity: 149/394 - (37%)
• Similarity: 225/394 - (57%)
• Gaps: 46/394 - (11%)

  Fly    33 QKVDKPSKDEKNVAKWLKKNVKTKKTKFLSHIVEYFTSSKAIDALLKSKFT---EGSNPLFTTRE 94
            |:|.:|||:||.|||:|:.|..||.|..:.|.|:||.:|||::.||.||:.   :|.:.||||||
Mouse    12 QEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVECLLDSKWAKAKKGEDALFTTRE 76

  Fly    95 QVIEFLDVMLEHKFFHRAKKV-------PVTLEEIRGKSGG----DKKADKEKTQDKEKDKAKDE 148
            .|:::.:.:|:.:|||||.||       .|..|:.:|||..    |||:.||..::::..|.|::
Mouse    77 SVVDYCNRLLKKQFFHRALKVMKMKYDKDVKKEKDKGKSESGKEDDKKSKKESVKEEKTKKEKEK 141

  Fly   149 KKDTDPEGDNGQGDGGASGNEKEKEKKEKKKRKIRLDMHPEQIFVDGSEAYVWIYDPIPLHYWIF 213
            |||.:.|....:...|.       .||::.|:|.:|:.|.:|:|:||:|.:||||||:.:..::.
Mouse   142 KKDGEKEDSKKEETPGT-------PKKKETKKKFKLEPHDDQVFLDGNEVFVWIYDPVHIKTFVM 199

  Fly   214 GFILLLGAVGICLFPLWPPLLRKGVYYLSIAAAGFLVFILALTIVRLIVFIIVWALTGGKLHFWI 278
            |.||::..:...||||||..:|.||||||:.|..|:..||.|.|.|.|:|:|:|.:|||:.|||.
Mouse   200 GLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAIARCILFLIIWLITGGRHHFWF 264

  Fly   279 FPNLTEDVSFFASFWPLYESNYNSDPNNSSAKTDKKSKSKDKKK---------EKESDAEDTAVD 334
            .||||.||.|..||.|||...|...  .:..|.|:||::|.::|         ||:.|.|.....
Mouse   265 LPNLTADVGFIDSFRPLYTHEYKGP--KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKGAP 327

  Fly   335 AD-------GDADGDVDAEVSTLEPEKIELIKEHDTDMEIRKRRKV-----GADDYEEDDVDEEE 387
            ||       |:...|.|::  ..|.::.:....:..|.|:..:.::     |..|.|:||.|.|.
Mouse   328 ADHGPEGSGGERHSDTDSD--RREDDRSQHSSGNGNDFEMITKEELEQQTDGDCDEEDDDKDGEL 390

  Fly   388 TKAQ 391
            .|:|
Mouse   391 RKSQ 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trp1	NP_723510.1	Sec62	108..299	CDD:461073	86/201 (43%)
Sec62	NP_001344457.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..167		20/67 (30%)
		Sec62	<170..285	CDD:461073	58/114 (51%)
		MSCRAMM_ClfA	<291..362	CDD:468110	16/72 (22%)