Protein Alignment CG42366 and SRPK

DIOPT Version :10

• Sequence 1: NP_723501.2
• Gene: CG42366 / 34319
• FlyBaseID: FBgn0259712
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Alignment Length: 799
• Identity: 162/799 - (20%)
• Similarity: 260/799 - (32%)
• Gaps: 233/799 - (29%)

  Fly     2 NRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKL-----SHPN 61
            :||..:.:||.|.:.||.|.........||||.:|...:..|.|.:  |:|.||.:     |:|.
  Fly   168 DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARD--EIKILKTVRETDPSNPR 230

  Fly    62 IVKLKEVIRE------NDT-LYFVFEYMKENLYQMI-KDRDTHLPEPELKSILFQVLTGLAFMHR 118
            ..|..:::.:      |.| :..|||.:.:||.::| |.....:|...:|:|..|||.||.::|.
  Fly   231 RHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHT 295

  Fly   119 -HGFFHRDLKPEN-LLCSG----------------------PDLIKIADFGLAREIRSRPPFTDY 159
             ....|.|:|||| |||..                      |.|:..|    .:|.| .||.|..
  Fly   296 CCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYPSLVSRA----PKEYR-EPPITGK 355

  Fly   160 VS--------TRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVL 216
            :|        .:..:..|:.....:|....|  ..|.|            ..:||..     ...
  Fly   356 MSKNRKKKLKKKAKKRMELFKQQRDYLEQAD--GQGAI------------NPNEVQN-----GDA 401

  Fly   217 GTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKY 281
            |..|.|::.|...:...:|.               ...|......|:..| .|::...||:.
  Fly   402 GISDADEYFDANSVEDNVHV---------------AAGQPSRKQREERKA-PPEQSEEAQEQ--- 447

  Fly   282 PYFHALKRISPTAATKANVRLNSKYAASNGHPVQSVSNNVLPVQEKLQAVTELLHQTNNNMNSHS 346
               ..|...:..|..|...:..:|...|.|.....:.|:....:......::..:.:|:..|:.|
  Fly   448 ---DPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKS 509

  Fly   347 NLGKNNNLAPKNGGVPRKYQPKLSFLTTSEMGAGSH----------ADSSSLVGGATVDGVPVPQ 401
            |...:..|..::.|.....:||      .|....:|          ::|.|.:...:|
  Fly   510 NTNSSGTLKGQSNGKKMPLRPK------QEKQGSNHQLNNNNSKPNSNSDSKISSGSV------- 561

  Fly   402 HQNGGESINDIYLNRNISQLFGLPAGPQ--HQQQQ-------QVH--------------HPNVSF 443
             :|...:.|..:.|   |.|...|..||  |:.::       .||              |.....
  Fly   562 -ENTSSATNGPHSN---STLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDI 622

  Fly   444 STTSSRNAGAIYVNGSHLSYD---TANMNAKNNAKFVVGASNGGY-YVPVARPS----------- 493
            .|...|:...|...|.:.|.|   ||.|        |...:.|.| :.|.:..|
  Fly   623 QTRQYRSLEVIIGAGYNTSADIWSTACM--------VFELATGDYLFEPHSGESYTRDEDHLAHI 679

  Fly   494 --LLGPDAKVYNVFSKVSASQAPPSLIVRQPQLQPEVAPAPMRLSGRSRAAAAVQDPKM---GAL 553
              ||||                               .|..:.|:|...|.:..:..::   ..|
  Fly   680 IELLGP-------------------------------IPREILLNGTYAAKSFTRSCELRNISGL 713

  Fly   554 KSDDLDLILGSKLKTSAK-----------------RQRNAKANILLEDLFGQLSMDSDSDGKYPH 601
            |...|..:|..|.:.|.|                 .:|...|..|...   .|..|:...|.:..
  Fly   714 KPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHP---WLRXDTMQPGCWLR 775

  Fly   602 -TVPPTQQAKSGKTSTGGHGAGARERDLF---GESYLPRPG------LRKKATQSSL-EVNNGSH 655
             |.|.|.....|..:..|.|.|.|.|...   |...:|..|      :...|:.::| .:::.:.
  Fly   776 ATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIAS 840

  Fly   656 ADSLAPNAQKEKPAVASSF 674
            ..:.|..|.|.:|.:.:.|
  Fly   841 TSAAAMAALKARPYLVAPF 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42366	NP_723501.2	STKc_MAK_like	4..284	CDD:270824	75/324 (23%)
SRPK	NP_001369087.1	Protein Kinases, catalytic domain	159..>318	CDD:473864	49/151 (32%)
		Protein Kinases, catalytic domain	<600..763	CDD:473864	35/204 (17%)