Protein Alignment CG4598 and AUH

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: XP_005252123.1
• Gene: AUH / 549
• HGNCID: 890
• Length: 349
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 68/254 - (26%)
• Similarity: 106/254 - (41%)
• Gaps: 19/254 - (7%)

  Fly    32 DKTGIATLTMNRP-PVNGLNLELLQDLKSSIDEIESNKS-RGLILTSSSSTIFSAGLDILEMYKP 94
            |...|..|.:||. ..|.|:..|::.|..::|.::|:|. |.:|:.|....||.||.|:.|..|.
Human    95 DHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKM 159

  Fly    95 DKDRIRAFWTQLQDTWLALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVPNFTIGLNETQLGI 159
            ....:..|.::::.....:....|||.|||:|.:..||..||.:|:.||...:..:||.||:|.|
Human   160 SSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI 224

  Fly   160 VAPQWFMASFLSVLPQRIAERALNQGRMFTTEEALKVGLIDETANNKEE---AIEKCVAFIGTFA 221
            :............:...:|:..:...|:...:||..||||.......:|   |..|.:.....|.
Human   225 IPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFL 289

  Fly   222 KVNPLARSLTKQQFRAADLQQLQNG-------------RKEDLEKFLFF-VNQPAVQKG 266
            ...|:|..:.|..........|..|             .|:.||..|.| ..:|...||
Human   290 PQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKG 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	54/189 (29%)
AUH	XP_005252123.1	crotonase-like	99..349	CDD:474030	67/250 (27%)