Protein Alignment CG4598 and HADHA

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_000173.2
• Gene: HADHA / 3030
• HGNCID: 4801
• Length: 763
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 79/329 - (24%)
• Similarity: 129/329 - (39%)
• Gaps: 84/329 - (25%)

  Fly     1 MMRSKVLSLVARAGSNRMM-----------STATKLTTVEVN--DKTGIATLTMNRP--PVNGLN 50
            |:..:.:.:::|..:.|::           .::..||...:|  .|..:|.:.:|.|  .||.|:
Human     1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLS 65

  Fly    51 LELLQDLKSSIDEI-ESNKSRGLILTSSSSTIFSAGLDILEMYKPDKDRIRAFWTQLQDTWLA-- 112
            .||..:....::|| .|::.|..:|.||....|.||.||        :.:.|..|..:.|.|:
Human    66 KELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADI--------NMLAACKTLQEVTQLSQE 122

  Fly   113 -------LYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVPN--FTIGLNETQLGIVAPQWFMAS 168
                   |..|:.|..|||||....||..:|.||:||:...:  ..:|..|..||.:..    |.
Human   123 AQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPG----AG 183

  Fly   169 FLSVLPQRIAERA----LNQGRMFTTEEALKVGLIDETAN--------NKEEAIEKCVAFIGTFA 221
            ....||:.:...|    :..||....:.|.|:||:|:...        .:|..||.......|||
Human   184 GTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFA 248

  Fly   222 ------KVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFLF---FVNQPAVQKGLGIYLEGLKKK 277
                  |::|                :...|..|.|..:..   ||.|...:|        :::|
Human   249 KGLADKKISP----------------KRDKGLVEKLTAYAMTIPFVRQQVYKK--------VEEK 289

  Fly   278 AKKQ 281
            .:||
Human   290 VRKQ 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	59/217 (27%)
HADHA	NP_000173.2	fa_ox_alpha_mit	27..762	CDD:131494	76/303 (25%)