Protein Alignment CG4598 and HIBCH

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 61/308 - (19%)
• Similarity: 114/308 - (37%)
• Gaps: 89/308 - (28%)

  Fly    22 ATKLTTVEVNDKTGIATLTMNRPP-VNGLNLELLQDLKSSIDEIESNKSRGL-ILTSSSSTIFSA 84
            |.:...:|....||:  :|:|||. :|.|.|.:::.:...:.:.|.:....| |:..:....|.|
Human    34 AAEEVLLEKKGCTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96

  Fly    85 GLDILEMYKPDKDRIRAFWTQLQDTWL---ALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVP 146
            |.||..:.:.:|.:.:......::.::   |:.....|..|.|:|.:..||..|:...::||...
Human    97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE 161

  Fly   147 NFTIGLNETQLGI--------VAPQ------WFMA------------------------------ 167
            .....:.||.:|:        ..|:      :|:|
Human   162 KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 226

  Fly   168 ------------SFLSVLPQRIAERALNQGRMFTTEEALKVGLIDE-----TANNKEEAIEKCVA 215
                        :..|||.....|..:::.:.|..||.:     |:     :||..||.||....
Human   227 EDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM-----DKINSCFSANTVEEIIENLQQ 286

  Fly   216 FIGTFA--------KVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFL 255
            ...:||        |::|.:..:|        |:||..|..:.|::.|
Human   287 DGSSFALEQLKVINKMSPTSLKIT--------LRQLMEGSSKTLQEVL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	49/255 (19%)
HIBCH	NP_055177.2	ECH_2	46..376	CDD:465024	59/296 (20%)