Protein Alignment CG4598 and ECI2

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_996667.2
• Gene: ECI2 / 10455
• HGNCID: 14601
• Length: 394
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 56/275 - (20%)
• Similarity: 101/275 - (36%)
• Gaps: 76/275 - (27%)

  Fly    14 GSNRMMSTATKLTTVEVNDKTGIATLTMNRP-PVNGLNLELLQDLKSSIDEIESNKSRGLILTSS 77
            |::|   .:|...|:.|..:.||..:..||| ..|.:|.|:..::..::.....:.|...:||.:
Human   131 GTDR---KSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGN 192

  Fly    78 SSTIFSAGLDIL-----------EMYKPDKDRIRAFWTQLQDTWLALYGSSV----PTAAAINGH 127
            .. .:|:|.|:.           |..|.:...:|.|           .|..:    |..|.:||
Human   193 GD-YYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREF-----------VGCFIDFPKPLIAVVNG- 244

  Fly   128 SPAGGCLLATSCEYRVMVPNFTIGLNETQLGIV--------------------APQWFMA-SFLS 171
             ||                   :|::.|.||:.                    :|:...: :|..
Human   245 -PA-------------------VGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPK 289

  Fly   172 VLPQRIAERALNQGRMFTTEEALKVGLIDETANNKEEAIEKCV-AFIGTFAKVNPLARSLTKQQF 235
            ::....|...|..|:..|..||...||:.|..  .:...:|.| ..:..|||:.|.|..::|:..
Human   290 IMSPAKATEMLIFGKKLTAGEACAQGLVTEVF--PDSTFQKEVWTRLKAFAKLPPNALRISKEVI 352

  Fly   236 RAADLQQLQNGRKED 250
            |..:.::|.....|:
Human   353 RKREREKLHAVNAEE 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	44/227 (19%)
ECI2	NP_996667.2	ACBP	39..113	CDD:469667
		crotonase-like	142..335	CDD:119339	43/227 (19%)
		ECH-like	151..322		38/205 (19%)
		Microbody targeting signal. /evidence=ECO:0000255	392..394