DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zf30C and wor

DIOPT Version :9

Sequence 1:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	647	Identity:	130/647 - (20%)
Similarity:	211/647 - (32%)	Gaps:	214/647 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 PREESRPMECKCCYTRFSSASNLSKHRRSR-------------PDT------------CGQPEYD 164
            |..:..|.|.:   .||.:|.|.:|.:.:|             ||.            .|..|::
  Fly    55 PEPQPVPTELR---RRFDAAMNQTKEQLARRIWEETREIARAFPDVFTREEIAKSLARLGYGEFE 116

  Fly   165 SPGSSDGMKKHKAFRKKDRNRDSDDEDTTSEESEDSDDDIPLASRLKTKLKQESQNSDSGDECPD 229
            .|                      .|:...|...:.:..:||
  Fly   117 LP----------------------PEEEVMEPEPEPEQHLPL----------------------- 136

  Fly   230 FEPNNSEDDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEG 294
                  ....|||      |.::|.|..|||.|.                          |.|..
  Fly   137 ------RYTRDAS------PTIIKAEPSDEEQFP--------------------------LRNYN 163

  Fly   295 DGLKPFESLKVEQGAGILDEIAAVPLVEVAE-EDVLELRGHQMEKPPGPRKRGRPPKEKIPVVKR 358
            :.|                      |..:|| ||.::::..:.|.||.|     .|:...|
  Fly   164 NNL----------------------LKSIAEYEDCMKMQNIKEEIPPIP-----SPQLFYP---- 197

  Fly   359 KYRKRNAPRSP--SPDDSSGTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKH 421
                   |.:|  .|:|.|.|.:||       |.|.:.:.|.........|... .|...|.:
  Fly   198 -------PPTPLAEPEDLSVTQRRV-------LSENMNLQNVARALLSMQHMAP-QHAPPPID-- 245

  Fly   422 LRDDHKLNEAEMKEIFKDVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVH------------- 473
            :.:|.:..:....:|....|::       ::|..|:|.|.....||.|.:.|
  Fly   246 MEEDQENQDINQLKIKSSNDLY-------YQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQ 303

  Fly   474 -GEDGKLTFKCPCYCNLFFATKEQATEHARAQHKE------LLYCEKCDKYMTGHDSLKNHERNF 531
             |..|.:..:.. :|....:...||...|.||..:      ..:|:.|.|..:.:..|..|:: |
  Fly   304 PGGSGAIVDQTE-FCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQ-F 366

  Fly   532 HSKKEPRSQQRNLI-CDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLH 595
            |......:|.:.:. |..|.|.:....:|..|:|:.  .||. .|.:|||..|...:|:.|:..|
  Fly   367 HCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTH--TLPC-KCPICGKAFSRPWLLQGHIRTH 428

  Fly   596 KADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHM-----TVHTGI 655
            ..:.|:.|..|.:.|..::..::|::| |:|.|.|.|..|.|.:.....|..|:     |..:|.
  Fly   429 TGEKPFSCQHCNRAFADRSNLRAHMQT-HSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGG 492

  Fly   656 KRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYE 717
            .    :..|..|. ...||.|.:|:.:  |..|........:|...|      :.|.|.||:
  Fly   493 P----SGSGGGFD-QQQLQQHLQVYEE--GHNPHQLYYAGSVGSSNG------EEEEGGEYQ 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368	5/17 (29%)
		C2H2 Zn finger	511..532	CDD:275370	5/20 (25%)
		COG5048	<523..>672	CDD:227381	40/154 (26%)
		C2H2 Zn finger	546..566	CDD:275368	6/19 (32%)
		C2H2 Zn finger	575..595	CDD:275368	7/19 (37%)
		C2H2 Zn finger	603..624	CDD:275368	5/20 (25%)
		C2H2 Zn finger	632..652	CDD:275368	6/24 (25%)
		C2H2 Zn finger	660..680	CDD:275368	5/19 (26%)
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	7/19 (37%)
		C2H2 Zn finger	317..334	CDD:275368	4/16 (25%)
		zf-C2H2	345..367	CDD:278523	5/22 (23%)
		C2H2 Zn finger	347..367	CDD:275368	5/20 (25%)
		PHA00732	379..>417	CDD:177300	12/40 (30%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-C2H2_8	405..482	CDD:292531	24/78 (31%)
		zf-C2H2	406..428	CDD:278523	7/22 (32%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		zf-H2C2_2	421..444	CDD:290200	6/22 (27%)
		zf-C2H2	434..456	CDD:278523	5/22 (23%)
		C2H2 Zn finger	436..456	CDD:275368	5/20 (25%)
		zf-H2C2_2	448..473	CDD:290200	9/25 (36%)
		C2H2 Zn finger	464..481	CDD:275368	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100