Protein Alignment Pka-C1 and YPK1

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_012796.1
• Gene: YPK1 / 853733
• SGDID: S000001609
• Length: 680
• Species: Saccharomyces cerevisiae
• Alignment Length: 355
• Identity: 142/355 - (40%)
• Similarity: 207/355 - (58%)
• Gaps: 20/355 - (5%)

  Fly     9 NKKVDAAETVKEF----------LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIV 63
            |...|:|.:::.:          |.:.....:.|..||  ...::|||:.:|.:|.||||:||.|
Yeast   302 NLSFDSAASIRLYNHHWITLDNGLGKINISIDYKPSRN--KPLSIDDFDLLKVIGKGSFGKVMQV 364

  Fly    64 QHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPG 128
            :.|.|:..||:|.:.|..:|...:|.|||.|:.:|..:..||:|.|::.|:....||.||.::.|
Yeast   365 RKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFING 429

  Fly   129 GEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAK- 192
            ||:|.||:|.|||....:|||.|:::.|.:.||.||::||||||||:|:|.||::.:.|||..|
Yeast   430 GELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKL 494

  Fly   193 --RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVS 255
              :...:|.|.||||||||||::|..||.||||||.||||:|||..|.||::.:...::|:||:.
Yeast   495 NMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ 559

  Fly   256 GKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPR 320
            ..:.||..|..|.||||..||..|.|:|.|  ..|.::|:|..:|:...|..:..|....|:.|.
Yeast   560 EPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPA 622

  Fly   321 CKGPGDTSNFDDYEEEALRISSTEKCAKEF 350
            .....||||||   ||..|....:....|:
Yeast   623 VSNSMDTSNFD---EEFTREKPIDSVVDEY 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	131/291 (45%)
YPK1	NP_012796.1	YPK1_N_like	116..342	CDD:212165	7/41 (17%)
		Protein Kinases, catalytic domain	352..663	CDD:473864	131/303 (43%)