Protein Alignment Pka-C1 and TPK3

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_012755.1
• Gene: TPK3 / 853688
• SGDID: S000001649
• Length: 398
• Species: Saccharomyces cerevisiae
• Alignment Length: 303
• Identity: 149/303 - (49%)
• Similarity: 214/303 - (70%)
• Gaps: 1/303 - (0%)

  Fly    35 RNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQ 99
            |:.:...:|.||:.::||||||||||.:::......:||:|.|.|..:|||||||||.:|:|:|.
Yeast    77 RDTSGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLS 141

  Fly   100 AIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLD 164
            .:..||::.:...|:|:..::||::|:.|||:||.|||..||..|.::||||::.||.||||..|
Yeast   142 IVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 206

  Fly   165 LIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGV 229
            :|||||||||:|:|..|::|:|||||||.|...|:||||||:|:|||::.:|.|||:||||:.||
Yeast   207 IIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGV 271

  Fly   230 LVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDI 294
            |:|||.|||.||:....::.||.|::.:::||..|..|.:|||:.|:..||::|.|||:.|..|:
Yeast   272 LIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDV 336

  Fly   295 KNQKWFASTDWIAIFQKKIEAPFIPRC-KGPGDTSNFDDYEEE 336
            ||..||....|..:..:.||.|:.|.. :|.||||.||.|.||
Yeast   337 KNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	144/289 (50%)
TPK3	NP_012755.1	STKc_PKA_like	86..376	CDD:270732	144/289 (50%)