Protein Alignment Pka-C1 and Rps6ka6

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_080225.2
• Gene: Rps6ka6 / 67071
• MGIID: 1914321
• Length: 860
• Species: Mus musculus
• Alignment Length: 324
• Identity: 117/324 - (36%)
• Similarity: 190/324 - (58%)
• Gaps: 20/324 - (6%)

  Fly    16 ETVKE--FLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKD---YYAMK 75
            |.|||  ..:..||.:|   :.:|.      .|:.:|.||.||||:|.:|:.|...|   .||||
Mouse   166 ELVKEIPITQHVKEGYE---KADPA------QFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMK 221

  Fly    76 ILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGR 140
            :|.|.. :|::....|..|:.||..:..||:|.|.|.|:....||::|:::.||::|:.|.|...
Mouse   222 VLRKAS-LKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVL 285

  Fly   141 FSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKR---VKGRTWTLC 202
            |:|...:||.|::.||.::||.|.::||||||||:|:|..|::|:||||.:|.   .:.:.::.|
Mouse   286 FTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFC 350

  Fly   203 GTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSD 267
            ||.||:|||::..:|::::.|||:.|||::||..|..||......:....|:..|:..|....::
Mouse   351 GTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAE 415

  Fly   268 LKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFD 331
            .:.|||.|.:.:...|.|:  .||.::|...:|||.||..:::::::.||.|....|.||..||
Mouse   416 AQSLLRMLFKRNPANRLGS--EGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	109/294 (37%)
Rps6ka6	NP_080225.2	STKc_RSK_N	193..507	CDD:270734	108/288 (38%)
		STKc_RSK_C	542..828	CDD:270993