Protein Alignment Pka-C1 and PRKCQ

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_005252553.1
• Gene: PRKCQ / 5588
• HGNCID: 9410
• Length: 740
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 116/308 - (37%)
• Similarity: 177/308 - (57%)
• Gaps: 9/308 - (2%)

  Fly    43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQ-AIQFPFL 106
            ::||...|.||.||||:|.:.:.|.|..::|:|.|.|..|:....||.|:.|||:|. |.:.|||
Human   411 IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 475

  Fly   107 VSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLK 171
            ..:...|:...||:.|:||:.||::..|::...:|....:.||||:|:|..::||...::|||||
Human   476 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLK 540

  Fly   172 PENLLIDSQGYLKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYE 233
            .:|:|:|..|::|:.|||..|.   ...:|.|.||||:|:||||:|.:.||.:||||:.|||:||
Human   541 LDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYE 605

  Fly   234 MAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQK 298
            |..|..||......:::..|......:|.....:.||||..|...:..||.|..    .||:...
Human   606 MLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVR----GDIRQHP 666

  Fly   299 WFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFD-DYEEEALRISSTEK 345
            .|...:|..:.:|:|:.||.|:.|.|.|.|||| ::..|..|:|..::
Human   667 LFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADR 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	113/293 (39%)
PRKCQ	XP_005252553.1	C1_nPKC_theta-like_rpt1	187..247	CDD:410384
		C1_nPKC_theta-like_rpt2	266..315	CDD:410387
		STKc_nPKC_theta	408..738	CDD:270770	116/308 (38%)