Protein Alignment Pka-C1 and air-1

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_505119.1
• Gene: air-1 / 179202
• WormBaseID: WBGene00000098
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 309
• Identity: 97/309 - (31%)
• Similarity: 161/309 - (52%)
• Gaps: 44/309 - (14%)

  Fly    22 LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLK 86
            ::||:|  |..|        :||||:..:.||.|.||.|.|.:.|.||...|:|:|.|.::::|
 Worm    30 VDQARE--ESCW--------SLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQL- 83

  Fly    87 QVEHTL-NEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRF-- 148
            .|.|.| .|..|...::.|.:::|..:|.|:..::::|:|...||:|:.|:     |:|..:.
 Worm    84 GVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQ-----SQPGHKVNE 143

  Fly   149 -----YAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGF------AKRVKGRTWTLC 202
                 :..|:..|..|.|...:|:||:||||||:||:..||:.|||:      :||     .|||
 Worm   144 VIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKR-----HTLC 203

  Fly   203 GTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSD 267
            ||.:|||||::.::.::..||.||:|:|::||..||.||......::..:|...|:..||.....
 Worm   204 GTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDG 268

  Fly   268 LKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAP 316
            ...|:..:::.:..:|     ..:.||....|......    ::.||.|
 Worm   269 AASLINAIIKKEPQER-----LPLVDIMAHPWIKEMKQ----REDIEVP 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	91/287 (32%)
air-1	NP_505119.1	STKc_Aurora	43..297	CDD:270909	87/269 (32%)