Protein Alignment Pka-C1 and Sgk3

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001362972.1
• Gene: Sgk3 / 171498
• RGDID: 620242
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 350
• Identity: 133/350 - (38%)
• Similarity: 195/350 - (55%)
• Gaps: 27/350 - (7%)

  Fly    18 VKEFLE-----QAKEEFEDKWRRN--------------PTNT--AALDDFERIKTLGTGSFGRVM 61
            |:.||:     ...:..||:..|:              ||..  |...||:.:|.:|.||||:|:
  Rat   113 VRAFLQMDSPRHQSDPSEDEDERSTPKPHSTSRNINLGPTGNPHAKPSDFDFLKVIGKGSFGKVL 177

  Fly    62 IVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRI-LQAIQFPFLVSLRYHFKDNSNLYMVLEY 125
            :.:.|....:||:|:|.|:.|:..|:.:|.:.|:.: |:.::.||||.|.|.|:....||.||::
  Rat   178 LAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDF 242

  Fly   126 VPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGF 190
            |.|||:|.||::...|.||.:|||||:|..|..|||.:.::||||||||:|:||.|::.:||||.
  Rat   243 VNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGL 307

  Fly   191 AKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEK 252
            .|.   :...|.|.||||||||||:|..:.|:..||||.||.::|||..|.|||:.....::|:.
  Rat   308 CKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDN 372

  Fly   253 IVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPF 317
            |:...:............:|..||:.:...|.| .|....:|:|..:|.|..|..:.||||..||
  Rat   373 ILHKPLNLRPGVSLTAWSILEELLEKNRQNRLG-AKEDFLEIQNHPFFESLSWTDLVQKKIPPPF 436

  Fly   318 IPRCKGPGDTSNFDD-YEEEALRIS 341
            .|...||.|..|||. :.||.:..|
  Rat   437 NPNVAGPDDIRNFDAVFTEETVPYS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	121/293 (41%)
Sgk3	NP_001362972.1	PX_CISK	12..120	CDD:132780	3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..157		5/35 (14%)
		STKc_SGK3	165..490	CDD:270755	121/297 (41%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		3/9 (33%)