Protein Alignment Pka-C1 and RSKR

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001167574.1
• Gene: RSKR / 124923
• HGNCID: 26314
• Length: 410
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 93/300 - (31%)
• Similarity: 157/300 - (52%)
• Gaps: 19/300 - (6%)

  Fly    47 ERIKTLG---TGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVS 108
            :::|.||   .||||.|:.|.....|..:|:|::.|.||::...|.....|..|.:.|..||:.|
Human   105 QQLKILGLVAKGSFGTVLKVLDCTQKAVFAVKVVPKVKVLQRDTVRQCKEEVSIQRQINHPFVHS 169

  Fly   109 LRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPE 173
            |...::...:|:::..|. ..:::|....||.|.|...|.:||::||...|||.|.:::||:|.|
Human   170 LGDSWQGKRHLFIMCSYC-STDLYSLWSAVGCFPEASIRLFAAELVLVLCYLHDLGIMHRDVKME 233

  Fly   174 NLLIDSQGYLKVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAA 236
            |:|:|.:|:||:||||.::.|.  .:.:|:|||.:|:|||::....||.|.|||:||||::.:|.
Human   234 NILLDERGHLKLTDFGLSRHVPQGAQAYTICGTLQYMAPEVLSGGPYNHAADWWSLGVLLFSLAT 298

  Fly   237 GYPPFFADQP-IQIYEKIVSGKVRFPSHFGSDLKDLLRNLL-QVDLTK-RYGNLKAGVNDIKNQK 298
            |..|..|::. :.:...:.......|:.....|..||..|| |..|.: ||      ::..:...
Human   299 GKFPVAAERDHVAMLASVTHSDSEIPASLNQGLSLLLHELLCQNPLHRLRY------LHHFQVHP 357

  Fly   299 WFASTDWIAIFQKKIEAPFIPRCK----GPGDTSNFDDYE 334
            :|....:.....:|....|:...:    ...:|..|||::
Human   358 FFRGVAFDPELLQKQPVNFVTETQATQPSSAETMPFDDFD 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	92/297 (31%)
RSKR	NP_001167574.1	STKc_AGC	115..359	CDD:270693	83/250 (33%)