Protein Alignment Apoltp and vtg3

DIOPT Version :10

• Sequence 1: NP_995670.2
• Gene: Apoltp / 34283
• FlyBaseID: FBgn0032136
• Length: 4333
• Species: Drosophila melanogaster
• Sequence 2: XP_073771593.1
• Gene: vtg3 / 30518
• ZFINID: ZDB-GENE-991019-2
• Length: 1265
• Species: Danio rerio
• Alignment Length: 1255
• Identity: 242/1255 - (19%)
• Similarity: 443/1255 - (35%)
• Gaps: 382/1255 - (30%)

  Fly    52 YKYQYTVAVRTEFAGSGDNSSDLLLKSDLEIFFPKPCEGYLRINDAKLYDTLDELNDNESDSSEK 116
            |||:..|.|..|.....:  |.|.|:...:|....|....|::::.
Zfish    44 YKYEGLVQVGRELPHLVE--SALKLRCTFKIIGESPHTFVLQVSNV------------------- 87

  Fly   117 TKEYDYYDNLANEE--SESQNYDNMHPKSSDFNVDLTKNL-------LRFAFHDGLISEVCPQEQ 172
              :::.::.:..:.  |.|:|              :||:|       :.|.|..|.|:::.....
Zfish    88 --DFEDFNGIPGKSVFSPSKN--------------ITKHLSAEISQPIIFEFSKGQITDIRTAPG 136

  Fly   173 ETPWVLNIKKGILSAFQNTMMRFDVDANTTETDVSGQCQVQYAL-EDTDSSYVTIRKTKDINSCR 236
            .:..|:||.:|||...|.|:..........|..:.|.||..|.: ||:::..:.:.:..||.:|:
Zfish   137 VSNTVVNIVRGILGFLQVTVKTTQSFYELIELGIHGLCQSSYTVDEDSNAKELIVTRIVDITNCQ 201

  Fly   237 Q-----------------RYATHSVLQTTPYTFRDDKTIWPILKSQSHCNLTIDNNVYKEIKCLE 284
            |                 :....||:.|..:|:        .:||      |.|.....:....|
Zfish   202 QPASLYRGMALAPEDKLSKQRGESVVSTVKHTY--------TVKS------TADGGQITKAFAQE 252

  Fly   285 THLLVPFSNASSGALTTSTSR----LKL-DGVESYSAGEFLEQNPELVERRATLVFDHTPAVKP- 343
            .....|| |...|.......|    ||: |..:....|:        |:.|..|::.....:||
Zfish   253 RQYFSPF-NVKGGNFRMLALRDIELLKVSDTTDKVVTGQ--------VQSRGNLMYKTNKDLKPI 308

  Fly   344 ------SHDEIKAARELLVEMCRVGFPNIQREFIDVFTNFLQTSKSLDYKTLSVL--LQRSASTC 400
                  .:|.:....:|:..:.:....::..|   ..|..|...:.:...||..|  |.:..|..
Zfish   309 PVVMLNLNDPVPKILDLIKRLAQANIYHVDSE---TSTEILDLIQLMRVTTLDNLEHLWKQVSGN 370

  Fly   401 EQGRNHLLE---------SLPFIGSTASYK--------------VMRDQIINEKLTKQMAHDWMT 442
            ::.|...|:         .|.|:  .|.||              |..:.:..|.::..:|.:
Zfish   371 DEHRRWFLDLVVEVTDERILKFL--EARYKAGDITANEAGQALVVAFNHLSAEPVSVALAQE--- 430

  Fly   443 ALSFITRPDEETLETFHSILEYAKNRLDAEYTLGATAVVHSFCKHHEACEENLRVQQIINLLETE 507
               |:|.|..::    |.:|...       ..|...::||.:|.:.:.|...: ||.::|:..:.
Zfish   431 ---FLTIPFSKS----HPLLWNT-------VVLAYGSLVHRYCVYTDPCPITV-VQPLLNMAASS 480

  Fly   508 FLNLYNLFKGERRTRERMVILLKGLGNIGVVSSAFAEQLQWIIR------EDEAPVDIRLHG--I 564
            .         .:.:.:.||:.||.|||...:||     ::.:::      .....:..|:.|  :
Zfish   481 L---------SKNSEDEMVLALKSLGNAAHLSS-----IKTLLKFLPGYSNGAEKLSTRVQGAAV 531

  Fly   565 LAFRRV-DCARH--RSYFLDNYGNYTLNSELRIYSYLQAMRC-PDYISVGVIKSILEHEEINQVG 625
            .|||.: ..|.|  :...|:.:....|.:|:|:.:.:..:.. |....:.|:..:|..|...||.
Zfish   532 QAFRLLASRAPHSVQDIVLNLFVQKHLPAEIRMLACIVLLETKPSTALISVVSEVLLEEADLQVA 596

  Fly   626 SFVWSHLTNLAKSNSPVRIEAQGLLLNDELSERFKMDIRK-------FSRNYEHSLFFDEYNFGT 683
            ||.:|.|...|||.:|   :.|.|.:...::  .|:..||       :|:|.....|.|::.|||
Zfish   597 SFSYSLLKGFAKSRTP---DNQHLSIACNIA--MKILTRKLGHLSYRYSKNLHFDWFHDDFLFGT 656

  Fly   684 TTDANVIFGTDSYLPRIASVNFTADLFGQSVNFFEFTARAEGLEELAANAFGPKGPLSGQLLRKK 748
            :.|..:: ..:|.:|....:.......|:.:.|.||..||:||::|.|.               |
Zfish   657 SADVYML-QNESPIPTKLMLKGKFHFIGRILQFLEFGIRADGLKDLFAG---------------K 705

  Fly   749 LSFLNRWLGNESAEEDDTLENLLSLDNLRLKRKAQEQARASEEEVDEDYDFEESLEGNKRQKRDV 813
            :..|.:.||         :.:|.|:    ||..:..|:...::.:...|
Zfish   706 IPELTKDLG---------ISDLASI----LKILSNWQSLPKDKPLLTAY---------------- 741

  Fly   814 STTRKQEIDRNVDSLGYKLKYDYNNPRAQFGLRVFGNDLRYFNVESLVEVMALAAKFNP------ 872
                                           .||||.:....:| |...|.::...|:|
Zfish   742 -------------------------------ARVFGQEAFLMDV-SRDSVQSIIKSFSPSAGKES 774

  Fly   873 --FQQAKNVLSGKEFTYTKSRVFLDASYTVPLAVGLPLAIHAFGA--SSIDLRVSGNLDEMDPPT 933
              :::.::|..|..:.:||..:..:|.:..|..:|||:.|..:.:  :::.::...   |::||.
Zfish   775 KVWERIQDVQKGTSWHWTKPHLVYEARFIQPTCLGLPVEISKYYSVVNAVTMKAKA---EINPPP 836

  Fly   934 DWHF------DVEGQFKPSVSVD----VITTMQTDMFWEQSGIKVKSNLYSNSELVAKLKVRGRN 988
            ..|.      |:..|....:.|.    :...:.||:|  |.|.::||.:.........||:..:.
Zfish   837 KEHLGELLSSDISMQTDGFIGVTKDHFLFHGINTDLF--QCGTELKSKVSMGLPWAFDLKINPKE 899

  Fly   989 LVSFSFDLPRDKN--EIFSVRS---------------------------------ELLVQKREEQ 1018
             ..:..:|...|:  |:|||.|                                 .:|...|:||
Zfish   900 -QKYEMNLTPSKSVTELFSVSSNVYAVSRNIEDPTSSKITPMMPETGESWQGVPLRMLPPLRDEQ 963

  Fly  1019 LPQAGIANRSANSTCTWPVLDQAIGLQMC-------SHYSVPDLSNATEIYPSLLLAGPLNFSLI 1076
            ..::|:..|.....       :..|..:|       :||        ...||...|.|..:||..
Zfish   964 TKKSGMKFRQCAEA-------KIYGTALCIEAEAKRAHY--------LHEYPLYYLLGDTHFSYS 1013

  Fly  1077 LKKS-----------DLSAKKY--------------VFEYKWDQ----QEEDNNFSLVFT----- 1107
            |:.:           .:||.:.              ||:.|.|:    :|...:.||..|
Zfish  1014 LEPAKDAKPIEKIQIQVSASRQHPSVMSGMVNLNQRVFKEKRDENTSCEERKTSSSLPVTQDLDV 1078

  Fly  1108 TPGSKVPRVLVANVTKVPDA 1127
            ||.   |.|.|..::..|.|
Zfish  1079 TPD---PVVTVKALSLSPQA 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Apoltp	NP_995670.2	LPD_N	49..633	CDD:214755	126/656 (19%)
		Vit_open_b-sht	665..1005	CDD:462702	69/368 (19%)
		DUF1081	1027..>1116	CDD:461916	25/129 (19%)
		VWD	3741..3908	CDD:214566
		C8	3952..4014	CDD:214843
vtg3	XP_073771593.1	None