Protein Alignment Toll-4 and RPP4

DIOPT Version :10

• Sequence 1: NP_523519.2
• Gene: Toll-4 / 34235
• FlyBaseID: FBgn0032095
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_193420.2
• Gene: RPP4 / 827395
• AraportID: AT4G16860
• Length: 1147
• Species: Arabidopsis thaliana
• Alignment Length: 908
• Identity: 186/908 - (20%)
• Similarity: 304/908 - (33%)
• Gaps: 341/908 - (37%)

  Fly   204 NGPKMVTFKYLYDSTV--NSVITNNYIRKTMNNTEKIKIYYHNTFEKTTLTMEKNIFHGKNKMSA 266
            ||.|:...|.|.:..|  ..:...:.||.|.:.    .|..||..||    :.:.|...|:|
plant   440 NGFKVSNVKELLEDDVGLTMLADKSLIRITPDG----DIEMHNLLEK----LGREIDRAKSK--- 493

  Fly   267 LIFNGLKIKGLTNNTFENL-----------TSLNTLIFDNVFLKDLSFLRSSTLQSSLTYCIMKV 320
              .|..|.:.|||  ||::           |.|...:...|.......|
plant   494 --GNPAKRQFLTN--FEDIQEVVTEKTGTETVLGIRVPPTVLFSTRPLL---------------- 538

  Fly   321 DNMVDLKSFEKFTNLEIIEVSQYKGFKNFT------------AFICEPYK-SHCKFTLGINEVAC 372
              :::.:||:...||:.:|:..:.....::            ..:..|.| ...|:..      |
plant   539 --VINEESFKGMRNLQYLEIGHWSEIGLWSEIGLWSKIDLPQGLVYLPLKLKLLKWNY------C 595

  Fly   373 PLKCNCSYNRDK---------SQLEIDCWQKNLTTIPSLPVPKKGSSALVFQSNLLAELPDNSLE 428
            |||...|..:.:         |:|| ..|:   .|:|...:.|.....    ||.|.|:||.||.
plant   596 PLKSLPSTFKAEYLVNLIMKYSKLE-KLWE---GTLPLGSLKKMDLGC----SNNLKEIPDLSLA 652

  Fly   429 GYHNLKSLDVSYNQLTSLSVSQLPESLHYLDIRHNKITTLSPQVV--------------EYLYSV 479
              .||:.|::|..:    |:..||.|:.    ...|:.||....|              ||| ||
plant   653 --INLEELNLSKCE----SLVTLPSSIQ----NAIKLRTLYCSGVLLIDLKSLEGMCNLEYL-SV 706

  Fly   480 NVFNQYGNKWSIYCDEYHLQEFFWYKAKLLRIKTSKFQTIMEY-IELSSKGSFVENFF-----VQ 538
            :..:..|.:..||... .|:..:|....:.|: .|.|:.  || :||..:.|.:|..:     :.
plant   707 DWSSMEGTQGLIYLPR-KLKRLWWDYCPVKRL-PSNFKA--EYLVELRMENSDLEKLWDGTQPLG 767

  Fly   539 NIDQLYLEANE--DEIID-----------AFG-------PSD-----KYFNLKLMEALNHAIWLF 578
            ::.::||..::  .||.|           .||       ||.     |..||.:.:.  ..:..|
plant   768 SLKEMYLHGSKYLKEIPDLSLAINLERLYLFGCESLVTLPSSIQNATKLINLDMRDC--KKLESF 830

  Fly   579 SGEFDEIILHHLN-SPCPYRCSCCFEWHTGEFLINCRNLSLDIYPRLPNSIPYKTTLYLDRNEIR 642
            ..:.:...|.:|| :.||                |.||     :|.:.....|...|. |||||
plant   831 PTDLNLESLEYLNLTGCP----------------NLRN-----FPAIKMGCSYFEILQ-DRNEI- 872

  Fly   643 KLTNTESLVVAGHASIHKLHMSQN----------LLRELPLHLLPENITYLDVRNNLLKYLDDGV 697
                          .:.....::|          |:|.:|....||.:|:|||.....:.|.:|:
plant   873 --------------EVEDCFWNKNLPAGLDYLDCLMRCMPCEFRPEYLTFLDVSGCKHEKLWEGI 923

  Fly   698 IAF-------LEYRENITKIE------------LSGNPWECNCKAKAFLSFLRRHEPMEYETVLR 743
            .:.       |...||:|:|.            |:|      ||:...|       |.....:.|
plant   924 QSLGSLKRMDLSESENLTEIPDLSKATNLKRLYLNG------CKSLVTL-------PSTIGNLHR 975

  Fly   744 RVEITDDKCPEDCICCVDTSNSDSLAYVVDCSGKELSEIPQLPTPTYGQTTLVFERNSLKKWPSS 808
            .|.:.                      :.:|:|.||     |||.....:.::.:
plant   976 LVRLE----------------------MKECTGLEL-----LPTDVNLSSLIILD---------- 1003

  Fly   809 LLPGYSSVTRFYLAHNRL-------SDIDQLPDKLEYLDISNNNFSALDDRVRGFLQKRMNSSQL 866
             |.|.||:..|.|...|:       :.|:::|             ..::|..|
plant  1004 -LSGCSSLRTFPLISTRIECLYLENTAIEEVP-------------CCIEDLTR------------ 1042

  Fly   867 QLSLFGNPWTCRCEDKDFLVFVKEQAKNIA-NASAIQCIDTGRSLIEVEETDICPSVLIYYTSLA 930
             ||:             .|::..::.|||: |...:      .||:..:.|| |..|
plant  1043 -LSV-------------LLMYCCQRLKNISPNIFRL------TSLMVADFTD-CRGV-------- 1078

  Fly   931 VSLLIIALSINVFICFRQPIMIWFYEHEICLSLAARRELDEDKKYDAFLS------FTHKDED 987
                |.|||....:...:       :|..|:.|:...|...::.:|....      |::||||
plant  1079 ----IKALSDATVVATME-------DHVSCVPLSENIEYTCERFWDELYERNSRSIFSYKDED 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-4	NP_523519.2	LRR	210..>470	CDD:443914	64/294 (22%)
		leucine-rich repeat	264..287	CDD:275380	7/33 (21%)
		leucine-rich repeat	288..308	CDD:275380	3/19 (16%)
		leucine-rich repeat	309..334	CDD:275380	2/24 (8%)
		leucine-rich repeat	335..386	CDD:275380	10/72 (14%)
		PRK15370	<381..>482	CDD:185268	32/123 (26%)
		leucine-rich repeat	388..408	CDD:275380	5/19 (26%)
		leucine-rich repeat	412..432	CDD:275378	8/19 (42%)
		LRR	<416..591	CDD:443914	53/219 (24%)
		leucine-rich repeat	433..454	CDD:275378	6/20 (30%)
		leucine-rich repeat	455..478	CDD:275378	7/36 (19%)
		leucine-rich repeat	479..490	CDD:275378	2/10 (20%)
		leucine-rich repeat	632..657	CDD:275378	6/24 (25%)
		leucine-rich repeat	658..679	CDD:275378	5/30 (17%)
		leucine-rich repeat	680..706	CDD:275378	7/32 (22%)
		PCC	684..>771	CDD:188093	17/105 (16%)
		leucine-rich repeat	707..719	CDD:275378	4/23 (17%)
		leucine-rich repeat	771..791	CDD:275380	7/19 (37%)
		PRK15370	<793..>877	CDD:185268	13/90 (14%)
		leucine-rich repeat	793..815	CDD:275378	2/21 (10%)
		leucine-rich repeat	816..835	CDD:275378	5/25 (20%)
		leucine-rich repeat	836..859	CDD:275378	2/22 (9%)
		TIR	974..1110	CDD:214587	6/20 (30%)
RPP4	NP_193420.2	PLN03210	13..>1081	CDD:215633	173/850 (20%)
		leucine-rich repeat	609..631	CDD:275380	6/25 (24%)
		leucine-rich repeat	632..654	CDD:275380	9/27 (33%)
		leucine-rich repeat	655..678	CDD:275380	7/30 (23%)
		leucine-rich repeat	679..700	CDD:275380	3/20 (15%)
		leucine-rich repeat	724..768	CDD:275380	11/46 (24%)
		leucine-rich repeat	746..763	CDD:275380	4/16 (25%)
		leucine-rich repeat	769..791	CDD:275380	5/21 (24%)
		leucine-rich repeat	792..815	CDD:275380	4/22 (18%)
		leucine-rich repeat	816..838	CDD:275380	3/23 (13%)
		leucine-rich repeat	906..928	CDD:275380	6/21 (29%)
		leucine-rich repeat	929..951	CDD:275380	5/21 (24%)
		leucine-rich repeat	952..975	CDD:275380	6/35 (17%)
		leucine-rich repeat	976..998	CDD:275380	8/48 (17%)
		leucine-rich repeat	1021..1042	CDD:275380	3/33 (9%)
		leucine-rich repeat	1043..1066	CDD:275380	7/41 (17%)